摘要
目的比较3D与2D腹腔镜下乙状结肠-直肠癌根治术治疗乙状结肠-直肠癌的效果。方法选取2018年6月至2021年6月收治的80例乙状结肠-直肠癌患者为研究对象,按照随机数字表法将其分为对照组和研究组,各40例。对照组采取2D腹腔镜下乙状结肠-直肠癌根治术治疗,研究组采取3D腹腔镜下乙状结肠-直肠癌根治术治疗。比较两组的病情控制效果、手术相关指标、白细胞分化抗原4阳性/白细胞分化抗原8阳性(CD4^(+)/CD8^(+))、活性氧(ROS)、总抗氧化能力(T-AOC)水平及并发症发生情况。结果研究组的病情控制总有效率为80.00%,高于对照组的55.00%,差异具有统计学意义(P<0.05)。研究组的术后首次排气时间、术后首次排便时间、术后尿管拔除时间、术后进流食时间短于对照组,差异具有统计学意义(P<0.05)。术后3 d,研究组的CD4^(+)/CD8^(+)及T-AOC水平高于对照组,ROS水平低于对照组,差异具有统计学意义(P<0.05)。研究组的排尿功能障碍、男性勃起功能障碍及男性射精功能障碍发生率低于对照组,差异具有统计学意义(P<0.05)。结论3D腹腔镜下乙状结肠-直肠癌根治术治疗乙状结肠-直肠癌的效果较好,可有效控制病情,促进患者术后恢复,且对免疫功能损伤较小,术后应激反应轻微,安全性高,值得推荐。
Objective To compare the effects of 3D and 2D laparoscopic radical resection of sigmoid colon-rectal cancer in the treatment of sigmoid colon-rectal cancer.Methods A total of 80 patients with sigmoid colon-rectal cancer admitted from June 2018 to June 2021 were selected as the research objects and divided into control group and study group according to the random number table method,with 40 cases in each group.The control group was treated with 2D laparoscopic radical resection of sigmoid colon-rectal cancer,and the study group was treated with 3D laparoscopic radical resection of sigmoid colon-rectal cancer.The disease control effect,operation related indexes,cluster of differentiation 4 positive/cluster of differentiation 8 positive(CD4^(+)/CD8^(+)),reactive oxygen species(ROS),total antioxidant capacity(T-AOC)levels and complications were compared between the two groups.Results The total effective rate of disease control in the study group was 80.00%,which was higher than 55.00%in the control group,and the difference was statistically significant(P<0.05).The postoperative first exhaust time,postoperative first defecation time,postoperative catheter removal time and postoperative feeding time in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).At 3 d after surgery,the CD4^(+)/CD8^(+)and T-AOC level in the study group were higher than those in the control group,the level of ROS was lower than that in the control group,and the differences were statistically significant(P<0.05).The incidences of urinary dysfunction,male erectile dysfunction and male ejaculatory dysfunction in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The 3D laparoscopic radical resection of sigmoid colon-rectal cancer in the treatment of sigmoid colon-rectal cancer has better effect,it can effectively control the disease and promote postoperative recovery of patients,and has less damage to immune function,with mild postoperative stress response and high safety,which is worthy of recommendation.
作者
秦占坤
柴源
魏星
QIN Zhankun;CHAI Yuan;WEI Xing(Gem Flower Xi'an Changqing Staff Hospital,Xi'an 710201;the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)
出处
《临床医学研究与实践》
2023年第26期49-52,共4页
Clinical Research and Practice
关键词
3D腹腔镜
2D腹腔镜
乙状结肠-直肠癌根治术
3D laparoscopy
2D laparoscopy
radical resection of sigmoid colon-rectal cancer
