摘要
目的探究负压封闭引流结合富血小板血浆对难愈性创面患者创面愈合及二期手术可能性的影响。方法选择2019年1月—2023年1月临沂市中心医院接诊的80例难愈性创面患者为研究对象,采用随机抽签法分为对照组(采取常规治疗)、观察组(在常规治疗基础上进行负压封闭引流技术、富血小板血浆联合治疗),各40例,对比两组疗效,包括临床总有效率、创面愈合时间、二期手术发生率,同时采用视觉模拟评分法(Visual Analogue Scale,VAS)、温哥华瘢痕评定量表(Vancouver Scar Scale,VSS)分别评价患者治疗前后疼痛程度、瘢痕增生状况。结果治疗后,观察组总有效率(95.00%)较对照组(77.50%)高,差异有统计学意义(χ^(2)=5.165,P<0.05)。观察组CRP、WBC较对照组低,差异有统计学意义(P<0.05)。观察组VAS评分、VSS评分较对照组低,创面愈合时间短于对照组,差异有统计学意义(P<0.05)。观察组二期手术发生率为2.50%较对照组的20.00%低,差异有统计学意义(P<0.05)。结论负压封闭引流、富血小板血浆的联合作用效果更理想,加速创面愈合,缓解疼痛程度,减轻瘢痕的形成,并降低二期手术发生率。
Objective To investigate the effect of negative pressure closed drainage combined with platelet-rich plasma on wound healing and the possibility of second-stage surgery in patients with difficult-to-heal wounds.Methods Eighty patients with refractory wounds treated in Linyi Central Hospital from January 2019 to January 2023 were selected as the study objects,and randomly divided into control group(conventional treatment)and observation group(combined treatment with negative pressure closed drainage technology and platelet-rich plasma on the basis of conventional treatment)by drawing lot,with 40 cases in each group.The efficacy of the two groups was compared,including clinical total effective rate,wound healing time,second-stage operation incidence,at the same time,Visual Analogue Scale(VAS)and Vancouver Scar Scale(VSS)were used to evaluate the pain degree and scar hyperplasia of patients before and after treatment.Results After treatment,the total effective rate of observation group(95.00%)was higher than that of control group(77.50%),and the difference was statistically significant(χ^(2)=5.165,P<0.05).CRP and WBC in observation group were lower than those in control group,and the difference was statistically significant(P<0.05).The scores of VAS and VSS in observation group were lower than those in control group,and wound healing time was shorter than that control group,the difference was statistically significant(P<0.05).The incidence of second stage operation in the observation group(2.50%)was lower than that in the control group(20.00%),and the difference was statistically significant(P<0.05).Conclusion The combined effect of negative pressure sealing drainage and platelet-rich plasma is more ideal,accelerating wound healing,relieving pain,reducing scar formation,and reducing the incidence of secondary surgery.
作者
宋增美
刘付存
唐公杰
SONG Zengmei;LIU Fucun;TANG Gongjie(Linyi Central Hospital,Linyi,Shandong Province,276400 China)
出处
《系统医学》
2023年第12期74-77,90,共5页
Systems Medicine
关键词
难愈性创面
负压封闭引流
富血小板血浆
创面愈合
二期手术可能性
Difficult-to-heal wound
Negative pressure closed drainage
Platelet-rich plasma
Wound healing
Possibility of second-stage surgery
