摘要
目的:探讨妊娠期轻中度缺铁性贫血(IDA)采用蛋白琥珀酸铁口服溶液的效果。方法:选取2021年2月—2022年6月枣庄市妇幼保健院收治的妊娠期轻中度IDA患者共计84例,根据随机数字表法分成研究组(n=42)与对照组(n=42),对照组采用多维铁口服溶液治疗,研究组采用蛋白琥珀酸铁口服溶液治疗,对比两组临床疗效、血液生化指标、铁代谢指标及不良反应。结果:研究组治疗总有效率(95.24%)较对照组(78.57%)更高(P<0.05);治疗4周后两组平均红细胞血红蛋白(MCH)、血红蛋白(Hb)、平均红细胞血红蛋白浓度(MCHC)、平均红细胞体积(MCV)水平均提高(P<0.05),研究组上述指标水平均较对照组更高(P<0.05);治疗4周后两组血清铁蛋白(SF)、血清铁(SI)、转铁蛋白饱和度(TSAT)水平均提高(P<0.05),研究组上述指标水平均较对照组更高(P<0.05);研究组不良反应发生率(7.14%)较对照组(23.81%)更低(P<0.05)。结论:蛋白琥珀酸铁口服溶液用于治疗妊娠期轻中度IDA,能够提高临床疗效,改善血液生化指标与铁代谢指标,降低不良反应发生率。
Objective:To explore the effect of Iron Proteinsuccinylate Oral Solution on mild to moderate iron deficiency anemia(IDA)during pregnancy.Method:A total of 84 patients with mild to moderate IDA during pregnancy who were admitted in Maternity and Child Health Care of Zaozhuang from February 2021 to June 2022 were selected,and divided into the study group(n=42)and the control group(n=42)by random number table method.The control group was treated with Multivitamin Iron Oral Solution,the study group was treated with Iron Proteinsuccinylate Oral Solution.The clinical efficacy,blood biochemical indicators,iron metabolism indicators and adverse reactions of the two groups were compared.Result:The total effective rate of the study group(95.24%)was higher than that of the control group(78.57%)(P<0.05).After 4 weeks of treatment,the levels of mean corpuscular hemoglobin(MCH),hemoglobin(Hb),mean corpuscular hemoglobin concentration(MCHC)and mean corpuscular volume(MCV)in both groups were increased(P<0.05),the above indexes of the study group were higher than those of the control group(P<0.05).After 4 weeks of treatment,the levels of serum ferritin(SF),serum iron(SI)and transferrin saturation(TSAT)in both groups were increased(P<0.05),the above indexes of the study group were higher than those of the control group(P<0.05).The incidence of adverse reactions in the study group(7.14%)was lower than that in the control group(23.81%)(P<0.05).Conclusion:The Iron Proteinsuccinylate Oral Solution in the treatment of mild to moderate IDA during pregnancy can improve the clinical efficacy,improve the blood biochemical indicators and iron metabolism indicators,and reduce the incidence of adverse reactions.
作者
王勇慧
霍娜娜
WANG Yonghui;HUO Nana(Maternity and Child Health Care of Zaozhuang,Shandong Province,Zaozhuang 277100,China;不详)
出处
《中国医学创新》
CAS
2023年第20期39-42,共4页
Medical Innovation of China
关键词
妊娠期轻中度缺铁性贫血
蛋白琥珀酸铁口服溶液
血液生化指标
Mild to moderate iron deficiency anemia during pregnancy
Iron Proteinsuccinylate Oral Solution
Blood biochemical indicators
