摘要
目的探讨颅内大血管急性闭塞患者应用静脉溶栓桥接动脉内取栓治疗的效果。方法将2019年1月-2021年12月在本院治疗的70例颅内大血管急性闭塞患者随机分为对照组和观察组,每组35例,对照组实施单纯静脉溶栓,观察组实施静脉溶栓桥接动脉内取栓,对比两组的血管再通情况及预后情况、治疗各指标、NIHSS评分变化。结果观察组血管再通率、预后良好率均高于对照组(P<0.05);观察组血管再通时间、住院时间均少于对照组,而并发症发生率、90d内死亡率低于对照组(P<0.05);观察组治疗后3d、7d、90d的NIHSS评分明显低于对照组(P<0.05)。结论颅内大血管急性闭塞患者应用静脉溶栓桥接动脉内取栓治疗的效果显著,能缩短血管再通时间,提高血管再通率,降低并发症及死亡率。
Objective To investigate and analyze effect of intravenous thrombolysis bridging intra-arterial thrombectomy in treatment of acute intracranial vascular occlusion.Methods The paper chose 70 patients with acute occlusion of intracranial large vessels treated in our hospital from January 2019 to December 2021,and divided them into two groups randomly.Control group was treated with simple intravenous thrombolysis,while observation group with intravenous thrombolysis bridging and intra arterial thrombectomy.Vascular recanalization and prognosis,treatment indicators and changes in NIHSS scores between two groups were compared.Results Vascular recanalization rate and good prognosis rate in observation group was higher than control group(P<0.05).Observation group had shorter vascular recanalization time and length of stay than control group,while incidence of complications and mortality within 90 days was lower than control group(P<0.05).The NIHSS scores of observation group were significantly lower than control group at 3,7 and 90 days after treatment(P<0.05).Conclusion Intravenous thrombolysis bridging for intra arterial thrombectomy can achieve significant effect for patients with acute occlusion of intracranial large blood vessels,can shorten time of vascular recanalization,improve rate of vascular recanalization and reduce complications and mortality.
作者
常成义
CHANG Chengyi(Neurology Department,Yingshang County Chengdong Hospital,Fuyang,Anhui 236299)
出处
《智慧健康》
2023年第14期89-92,共4页
Smart Healthcare
关键词
颅内大血管急性闭塞
静脉溶栓桥接动脉内取栓
单纯静脉溶栓
Acute occlusion of intracranial large vessels
Intraarterial thrombolysis bridging for thrombectomy
Effect
