摘要
目的对比超声造影剂不同注射方式对乳腺癌前哨淋巴结(SLN)检出率、显影时间的影响,评估显影时间预测SLN性质的诊断价值。方法收集于我院行麦默通微创旋切术并经病理检查确诊的乳腺癌患者40例,术前均行超声造影检查定位SLN,根据超声造影不同注射方式将患者分为试验组和对照组各20例,试验组采取乳晕区1个位点皮下注射法,对照组采取乳晕区4个位点皮下注射法,比较两组SLN检出率及平均显影时间。所有患者均行SLN活检,比较SLN活检阳性与阴性患者平均显影时间。结果试验组SLN检出率为90%,平均显影时间为(1.08±1.03)min;对照组SLN检出率为85%,平均显影时间为(1.24±1.23)min,两组SLN检出率及平均显影时间比较差异均无统计学意义。SLN活检阳性与阴性患者平均显影时间分别为(2.16±1.55)min、(0.76±0.53)min,二者比较差异有统计学意义(P<0.05)。结论超声造影不同注射方式对SLN检出率、显影时间均无明显影响;乳腺癌SLN的超声造影显影时间可作为评估SLN转移的参考指标之一。
Objective To compare the effect of different injection methods of ultrasound contrast agent on the detection rate and arrival time of breast cancer sentinel lymph nodes(SLN),and to evaluate the diagnostic value of enhance arrival time in predicting the nature of SLN.Methods A total of 40 patients with breast cancer were diagnosed by pathologic examination after mammotome minimally invasive biopsy in our hospital were collected,and contrast-enhanced ultrasound was performed to locate SLN before operation.Patients were divided into experimental group and control group according to different injection methods of ultrasound contrast agent,20 cases of each group.Subcutaneous injection at 1 site in the areolar region was performed in the experimental group,and subcutaneous injection at 4 sites in the areolar region was performed in the control group.The detection rate and average arrival time of SLN were compared between the two groups.SLN biopsy was performed in all patients,and the average arrival time was compared between positive and negative SLN biopsy patients.Results The detection rate of SLN in the experimental group was 90%,and the average arrival time was(1.08±1.03)min.In the control group,the detection rate of SLN was 85%,the average arrival time was(1.24±1.23)min.There were no significant differences in the detection rate and average arrival time of SLN between the two groups.The average arrival time of SLN biopsy positive and negative patients were(2.16±1.55)min and(0.76±0.53)min,respectively,and the difference between the two was statistically significant(P<0.05).Conclusion Different injection methods of ultrasound contrast agent had no significant effect on the detection rate and arrival time of SLN.The arrival time of contrast-enhanced ultrasound of SLN in breast cancer can be used as a reference index to evaluate SLN metastasis.
作者
林周谊
冉海涛
LIN Zhouyi;RAN Haitao(Department of Ultrasound,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)
出处
《临床超声医学杂志》
CSCD
2023年第7期514-517,共4页
Journal of Clinical Ultrasound in Medicine
基金
国家自然科学基金面上项目(82071926)。
关键词
超声检查
造影剂
注射方式
显影时间
乳腺癌
前哨淋巴结
Ultrasonography
Contrast agent
Injection methods
Enhance arrival time
Breast cancer
Sentinel lymph node
