摘要
目的探究心电图复极参数结合超敏C⁃反应蛋白(hs⁃CRP)、肌红蛋白(MYO)、心肌肌钙蛋白T(cTnT)检测对老年急性心肌梗死(AMI)的早期诊断效果。方法选择2019年3月至2022年5月期间芜湖市第五人民医院接治的82例老年急性心肌梗死患者作为AMI组,另选取75例经冠状动脉造影检测后排除AMI的因胸闷、胸痛入院患者作为非AMI组,对比两组患者及不同心功能分级的AMI患者的心电图复极参数、hs⁃CRP、MYO、cTnT检测结果,并分析其诊断效能。结果AMI组胸导联及肢体导联的QTc间期、QT间期、T波时间明显长于非AMI组,差异有统计学意义(P<0.05);AMI组hs⁃CRP、MYO、cTnT水平明显高于非AMI组,差异有统计学意义(P<0.05);不同心功能分级的AMI患者胸导联及肢体导联的QTc间期、QT间期、T波时间及hs⁃CRP、MYO、cTnT水平:Ⅱ级<Ⅲ级<Ⅳ级,差异有统计学意义(P<0.05);心电图复极参数+hs⁃CRP+MYO+cTnT联合检测的灵敏度、准确度等明显高于各指标单项检测的诊断效能(P<0.05)。结论心电图复极参数结合hs⁃CRP、MYO、cTnT检测对老年AMI患者早期诊断价值较高,值得推广应用。
Objective To explore the early diagnosis effects of electrocardiogram repolarization parameters combined with hypersensitive C⁃reactive protein(hs⁃CRP),myoglobin(MYO),cardiac troponin T(cTnT)detection in elderly patients with acute myocardial infarction(AMI).Methods 82 elderly patients with acute myocardial infarction admitted to Wuhu Fifth People's Hospital from March 2019 to May 2022 were selected as the research subjects of the AMI group,and another 75 patients admitted for chest tightness and chest pain who were excluded from AMI by coronary angiography were selected as the research subjects of the non⁃AMI group,the ECG repolarization parameters,hs⁃CRP,MYO,and cTnT detection results were compared between the two groups of patients and the AMI patients with different cardiac function grades,and their diagnostic efficacy was analyzed.Results The QTc interval,QT interval and T wave time of the chest leads and limb leads in the AMI group were significantly longer than those in the non⁃AMI group,and the difference was statistically significant(P<0.05).The levels of hs⁃CRP,MYO and cTnT in the AMI group were significantly higher than those in the non⁃AMI group,and the difference was statistically significant(P<0.05).The QTc interval,QT interval,and T wave time and hs⁃CRP,MYO,cTnT levels of chest leads and limb leads of AMI patients with different cardiac function grades:gradeⅡ<gradeⅢ<gradeⅣ,and the difference was statistically significant(P<0.05).The sensitivity and accuracy of combined detection of ECG repolarization parameters+hs⁃CRP+MYO+cTnT were significantly higher than the diagnostic efficiency of individual detection of each indicator(P<0.05).Conclusion ECG repolarization parameters combined with hs⁃CRP,MYO,and cTnT detection have a high value in early diagnosis of elderly AMI patients,and are worthy of popularization and application.
作者
丁佩芳
张钰婕
万标
DING Peifang;ZHANG Yujie;WAN Biao(Department of ECG Function,Wuhu Fifth People's Hospital,Wuhu,Anhui,China,241000)
出处
《分子诊断与治疗杂志》
2023年第5期880-883,共4页
Journal of Molecular Diagnostics and Therapy
基金
安徽省重点研究与开发计划项目(190410804032)。
