摘要
目的探讨原发性肝癌经导管肝动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)患者接受腕踝针治疗的效果以及对疼痛的影响。方法随机选取2021年5月—2022年7月福建中医药大学附属第三人民医院消化科收治的70例原发性肝癌TACE术患者作为研究对象,将其分为参照组和治疗组(每组35例),前者行常规止痛药物治疗,后者在常规止痛药治疗的基础上给予腕踝针治疗。比较两组疼痛缓解指标、疼痛缓解评分、生存质量、血清P物质含量、治疗有效率以及不良反应发生率。结果相较参照组,治疗组镇痛起效时间(6.56±2.12)min更短,镇痛持续时间(10.21±2.43)h更长,疼痛爆发频率(1.44±0.32)次/d更少,差异有统计学意义(t=19.872,13.065,19.426,P<0.001)。治疗前,两组术后NRS评分、KPS评分、血清P物质含量比较,差异无统计学意义(P>0.05),治疗后,两组指标优于治疗前(P<0.05),相较参照组,治疗组术后NRS评分、血清P物质含量更低,KPS评分更高,差异有统计学意义(t=3.409,12.971,6.860,P<0.001)。相较参照组40.00%,治疗组镇痛有效率65.71%更高,差异有统计学意义(χ^(2)=4.644,P=0.031),两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论原发性肝癌TACE术患者接受腕踝针治疗可更快速镇痛,持续时间长,有效缓解术后疼痛感,降低血清P物质含量,不易增加不良反应。
Objective To explore the therapeutic effect of transcatheter arterial chemoembolization(TACE)on primary liver cancer patients treated by wrist and ankle needle and its effect on pain.Methods Seventy patients enrolled in the Department of Gastroenterology of the Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine from May 2021 to July 2022 were randomly selected as research objects and divided into control group and treatment group(35 cases in each group).The former was treated with conventional analgesic drugs,while the latter was treated with wrist and ankle needle on the basis of conventional analgesic drugs treatment.Pain relief index,pain relief score,quality of life,serum substance P content,effective rate and incidence of adverse reactions were compared between the two groups.Results Compared with the control group,the analgesic onset time was shorter(6.56±2.12)min,the analgesic duration was longer(10.21±2.43)h,and the frequency of pain outbreak was less(1.44±0.32)time/d in the treatment group,and the difference was statistically significant(t=19.872,13.065,19.426,P<0.001).Before treatment,there was no statistically significant difference in postoperative NRS score,KPS score and serum substance P content between the two groups(P>0.05).After treatment,the two groups of indicators were significantly better than before treatment,and the difference was statistically significant(P<0.05).Compared with the control group,the NRS score and serum substance P content in the treatment group were lower and the KPS score was higher,and the difference was statistically significant(t=3.409,12.971,6.860,P<0.001).Compared with the control group(40.00%),the analgesic effective rate in the treatment group 65.71%was higher,and the difference was statistically significant(χ^(2)=4.644,P=0.031).There was no statistically significant difference in the incidence of adverse reactions between two groups(P>0.05).Conclusion TACE treatment for primary liver cancer patients with wrist and ankle needle can provide more rapid analgesia,long duration,effective relief of postoperative pain,reduce serum substance P content,and is not easy to increase adverse reactions.
作者
李海秀
祖水玲
刘武平
陈晓丹
陈凯丽
LI Haixiu;ZU Shuiling;LIU Wuping;CHEN Xiaodan;CHEN Kaili(Department of Gastroenterology,Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou,Fujian Province,350100 China)
出处
《中外医疗》
2023年第13期33-36,41,共5页
China & Foreign Medical Treatment
基金
福建中医药大学校管科研课题(XB2021037)。
关键词
原发性肝癌
腕踝针
不良反应
Primary liver cancer
Wrist and ankle needle
Adverse reations
