摘要
Crimean-Congo hemorrhagic fever(CCHF),caused by Crimean-Congo hemorrhagic fever virus(CCHFV),is endemic in Africa,Asia,and Europe,but CCHF epidemiology and epizootiology is only rudimentarily defined for most regions.Here we summarize what is known about CCHF in Central,Eastern,and South-eastern Asia.Searching multiple international and country-specific databases using a One Health approach,we defined disease risk and burden through identification of CCHF cases,anti-CCHFV antibody prevalence,and CCHFV isolation from vector ticks.We identified 2313 CCHF cases that occurred in 1944–2021 in the three examined regions.Central Asian countries reported the majority of cases(2,026).In Eastern Asia,China was the only country that reported CCHF cases(287).In South-eastern Asia,no cases were reported.Next,we leveraged our previously established classification scheme to assign countries to five CCHF evidence levels.Six countries(China,Kazakhstan,Kyrgyzstan,Tajikistan,Turkmenistan,and Uzbekistan)were assigned to level 1 or level 2 based on CCHF case reports and the maturity of the countries’surveillance systems.Two countries(Mongolia and Myanmar)were assigned to level 3 due to evidence of CCHFV circulation in the absence of reported CCHF cases.Thirteen countries in Eastern and South-eastern Asia were categorized in levels 4 and 5 based on prevalence of CCHFV vector ticks.Collectively,this paper describes the past and present status of CCHF reporting to inform international and local public-health agencies to strengthen or establish CCHFV surveillance systems and address shortcomings.
作者
Mohammad Fereidouni
Dmitry AApanaskevich
David B.Pecor
Natalia Yu.Pshenichnaya
Gulzhan NAbuova
Farida H.Tishkova
Yekaterina Bumburidi
曾宪坤
Jens H.Kuhn
Maryam Keshtkar-Jahromi
Mohammad Fereidouni;Dmitry AApanaskevich;David B.Pecor;Natalia Yu.Pshenichnaya;Gulzhan NAbuova;Farida H.Tishkova;Yekaterina Bumburidi;Xiankun Zeng;Jens H.Kuhn;Maryam Keshtkar-Jahromi(Jahrom University of Medical Sciences(دانشگاهعلومپزشكيخدماتبهداشتیدرمانیجهرم),Jahrom,Fars Province,74148-46199,Iran;U.S.National Tick Collection,The James H.Oliver Jr.Institute for Coastal Plain Science,Georgia Southern University,Statesboro,GA 30458,USA;Zoological Institute of Russian Academy of Sciences(ЗоологическийинститутРоссийскойакадеМиинаук),199034,St.Petersburg,Russia;Walter Reed Biosystematics Unit,Department of Entomology,Smithsonian Institution,Suitland,MD 20746-2863,USA;One Health Branch,Walter Reed Army Institute of Research,Silver Spring,MD 20910,USA;Central Research Institute of Epidemiology(Центральныйнаучно-исследовательскийинститутэпидеМиологии),111123,Moscow,Russia;South Kazakhstan Medical Academy(ОңтүстікҚазақстанМедицинаакадеМиясы),Shymkent,160016,Kazakhstan;Tajik Science and Research Institute of Preventive Medicine(ИнститутиилМй-тадкикотиитиббипрофилактикииТоцикистон),734025 Dushanbe,Tajikistan;Central Asian Office,Centers for Disease Control and Prevention,Almaty,050010,Kazakhstan;United States Army Medical Research Institute of Infectious Diseases,Fort Detrick,Frederick,MD 21702,USA;Integrated Research Facility at Fort Detrick,Division of Clinical Research,National Institute of Allergy and Infectious Diseases,National Institutes of Health,Frederick,MD 21702,USA;Division of Infectious Diseases,Department of Medicine,Johns Hopkins University School of Medicine,Baltimore,MD 21205,USA)
基金
supported in part through Laulima Government Solutions,LLC,prime contract with the U.S.National Institute of Allergy and Infectious Diseases(NIAID)under Contract No.HHSN272201800013C
J.H.K.performed this work as an employee of Tunnell Government Services(TGS),a subcontractor of Laulima Government Solutions,LLC,under Contract No.HHSN272201800013C.
