摘要
目的:分析液基细胞学联合细胞蜡块免疫组化技术对卵巢浆液性癌腹腔积液的诊断价值。方法:120例卵巢浆液性癌患者腹腔积液标本,均行传统细胞学涂片、液基细胞学制片技术、细胞蜡块免疫组化技术以及液基细胞学联合细胞蜡块免疫组化技术检测浆液性癌细胞,比较各种检测方法的诊断结果。结果:液基细胞学联合细胞蜡块免疫组化技术浆液性癌细胞检出率93.3%,高于传统细胞学涂片技术(55.0%)、液基细胞学涂片技术(76.7%)及细胞蜡块免疫组化技术(87.5%),差异均具有统计学意义(P<0.001)。结论:液基细胞学联合细胞蜡块免疫组化技术简单、易行,可以极大提高腹腔积液中卵巢浆液性癌细胞的检出率,有助于临床判断肿瘤恶性程度,制定治疗方案,值得临床推广应用。
Objective:To analyze the diagnostic value of liquid-based cytology combined with cell block immunohistochemistry in peritoneal effusion of ovarian serous carcinoma.Methods:120 peritoneal effusion specimens from patients with ovarian serous carcinoma were all examined by traditional cytology smear,liquid-based cytology,cell block immunohistochemistry and liquid-based cytology combined with cell block immunohistochemistry techniques.The diagnostic results of various detection methods were compared.Results:The detection rate of serous cancer cells by liquid-based cytology combined with cell block immunohistochemistry technique was 93.3%,which was significantly higher than that by traditional cytology smear technique(55.0%),liquid-based cytology technique(76.7%)and cell block immunohistochemistry technique(87.5%)(P<0.001).Conclusion:The technique of liquid-based cytology combined with cell block immunohistochemistry is simple and feasible,which can greatly improve the detection rate of ovarian serous cancer cells in peritoneal effusion and is helpful for clinical judgment of tumor malignancy and formulation of treatment plans.The technique is worthy of clinical promotion and application.
作者
姜晨霞
管小松
张曙
王燕
JIANG Chenxia;GUAN Xiaosong;ZHANG Shu;WANG Yan(Department of Pathology,Affiliated Hospital of Nantong University,Jiangsu 226001;Nantong Traceable Pathological Diagnosis Center)
出处
《交通医学》
2023年第1期39-42,共4页
Medical Journal of Communications
关键词
卵巢浆液性癌
腹腔积液
液基细胞学
细胞蜡块
免疫组化
ovarian serous carcinoma
peritoneal effusion
liquid-based cytology
cell block
immunohistochemistry
