摘要
目的探讨人乳头瘤病毒(HPV)感染现状及相关影响因素,为制定云南省德宏州相应预防HPV感染策略提供证据支持。方法选取2021年11月至12月德宏州芒市及梁河地区765例女性(包括阿昌族、傣族、德昂族、汉族、景颇族、傈僳族)进行子宫颈HPV检测,分析HPV感染相关因素,包含年龄、民族、吸烟史、性伴侣数、初次性生活年龄、流产次数、分娩次数、居住地、子宫颈柱状上皮外移情况;对有意义的因素进行多因素logistic回归分析。结果765例女性HPV总体人群感染率为10.8%(83/765),其中阿昌族感染率为8.7%(8/92),傣族感染率为11.6%(16/138),德昂族感染率为13.9%(20/144),汉族感染率为11.7%(17/145),景颇族感染率为8.7%(15/172),傈僳族感染率为9.5%(7/74)。影响HPV感染的相关因素包括性伴侣数(χ^(2)=5.848,P<0.05)和子宫颈柱状上皮外移(χ^(2)=5.646,P<0.05);进一步行多因素logistic回归分析提示:性伴侣数(OR=1.943)及子宫颈柱状上皮外移情况(OR=1.723)均为HPV感染的独立危险因素(P<0.05)。结论性伴侣数和子宫颈柱状上皮外移是子宫颈HPV感染的危险因素,倡导单一性伴侣及定期妇科检查对降低HPV感染率有重要意义。
Objective To analyze the current status of human papillomavirus(HPV)infection and related influencing factors and to provide evidence to develop the corresponding prevention strategy of HPV infection in Dehong of Yunnan Province.Methods From November 2021 to December 2021,765 women(including Achang,Dai,Deang,Han,Jingpo and Lisu ethnic groups)in Mangshi and Lianghe areas of Dehong Prefecture were selected for cervical HPV testing.HPV-related factors were analyzed,including age,ethnicity,smoking history,number of sexual partners,age at first sex,number of abortion,number of deliveries,residence,and cervical columnar epithelial migration,and logistic regression analysis were performed for significant univariates.Results The overall population infection rate was 10.8%(83/765),among which the infection rate of the Achang ethnic group was 8.7%(8/92),the infection rate of Dai nationality was 11.6%(16/138),the infection rate of Deang was 13.9%(20/144),the infection rate of the Han nationality was 11.7%(17/145),the incidence rate of Jingpo nationality was 8.7%(15/172),and the infection rate of Lisu nationality was 9.5%(7/74).Related factors affecting HPV infection included the number of sexual partners(x*=5.848,P<0.05)and migration of cervical columnar epithelium(x=5.646,P<0.05).Further logistic regression analysis showed that the number of sexual partners(OR=1.943)and the cervical columnar epithelial migration(OR=1.723)were all independent risk factors for HPV infection(P<0.05).Conclusion The number of sexual partners and cervical cylindrical epithelial migration are the risk factors for cervical HPV infection.A single sexual partner and regular gynecological examination can reduce cervical HPV infection.
作者
杨玉崟
彭泱泱
唐玲
王璐
刘宝兰
杨庆东
尹锦芳
许湘盈
李姚
罗祥美
YANG Yu-yin;PENG Yang-yang;TANG Ling;WANG Lu;LIU Bao-lan;YANG Qing-dong;YIN Jin-fang;XU Xiang-ying;LI Yao;LUO Xiang-mei(Dehong Hospital Affiliated to Kunming Medical University,Mangshi 678400,China)
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2023年第3期350-352,共3页
Chinese Journal of Practical Gynecology and Obstetrics
基金
云南省科技厅昆明医科大学联合专项重点项目(202001AY070001-171)。
