摘要
目的探讨卡前列素氨丁三醇注射液联合Bakri球囊宫腔填塞术治疗难治性产后出血的临床效果。方法选取2020年3月至2022年3月我院收治的60例难治性产后出血患者为研究对象,按照随机数字表法将其分为对照组和观察组,各30例。对照组给予子宫动脉栓塞术治疗,观察组给予卡前列素氨丁三醇注射液联合Bakri球襄宫腔填塞术治疗。比较两组的临床指标、卵巢功能指标、月经情况、子宫切除率、产褥感染率及生活质量。结果观察组的止血时间短于对照组,总失血量、住院费用少于对照组(P<0.05)。治疗后42 d,观察组的卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E2)水平高于对照组(P<0.05)。观察组的首次月经恢复时间短于对照组(P<0.05);两组的首次月经量、月经周期及月经天数比较,差异无统计学意义(P>0.05)。两组的子宫切除率、产褥感染率比较,差异无统计学意义(P>0.05)。治疗后42 d,观察组的健康调查简表(SF-36)各维度评分高于对照组(P<0.05)。结论卡前列素氨丁三醇注射液联合Bakri球囊宫腔填塞术用于难治性产后出血的治疗中,可快速止血,减少患者失血量,节省住院费用,促进月经恢复,提高生活质量。
Objective To explore the clinical effect of carboprost tromethamine injection combined with Bakri balloon intrauterine tamponade in the treatment of refractory postpartum hemorrhage.Methods Sixty patients with refractory postpartum hemorrhage admitted in our hospital from March 2020 to March 2022 were selected as the research objects.The patients were divided into control group and observation group according to the random number table method,with 30 cases in each group.The control group was treated with uterine artery embolization,and the observation group was treated with carboprost tromethamine injection combined with Bakri balloon intrauterine tamponade.The clinical indexes,ovarian function indexes,menstruation,hysterectomy rate,puerperal infection rate and quality of life were compared between the two groups.Results The hemostasis time of the observation group was shorter than that of the control group,and the total blood loss and hospitalization expenses were less than those of the control group(P<0.05).After 42 d of treatment,the levels of follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)in the observation group were higher than those in the control group(P<0.05).The first menstrual recovery time of the observation group was shorter than that of the control group(P<0.05);there were no significant differences in the first menstrual volume,menstrual cycle and menstrual days between the two groups(P>0.05).There were no significant differences in hysterectomy rate and puerperal infection rate between the two groups(P>0.05).At 42 d after treatment,the scores of each dimension of the MOS 36-Item Short Form Health Survey(SF-36)in the observation group were higher than those in the control group(P<0.05).Conclusion Carboprost tromethamine injection combined with Bakri balloon intrauterine tamponade in the treatment of refractory postpartum hemorrhage can quickly stop bleeding,reduce blood loss,save hospitalization expenses,promote menstrual recovery and improve quality of life.
作者
尚韦韦
杨晓棠
SHANG Weiwei;YANG Xiaotang(Gynecology and Obstetrics Department,Zhangye People's Hospital Affiliated to Hexi University,Zhangye 734000,China)
出处
《临床医学研究与实践》
2023年第9期111-114,共4页
Clinical Research and Practice
基金
河西学院青年教师科研基金项目(No.QN2021012)。
