摘要
目的分析肠内序贯营养支持在老年重症脑卒中病人中的应用效果。方法将2016年6月至2019年6月期间利辛县人民医院收治的80例老年重症脑卒中病人按随机数字表法分为对照组(n=40)和研究组(n=40),分别给予常规肠内营养支持和肠内序贯营养支持。于入院时和治疗14 d时检测病人营养状态指标以及神经功能。出院后6个月采用Barthel指数(BI)评价病人生活质量。结果两组病人治疗14 d时血清白蛋白(Alb)、前白蛋白(PA)水平较入院时均明显降低(P<0.05),研究组病人治疗14 d时血清Alb[(35.24±3.18)g/L比(30.16±3.52)g/L]、PA[(216.17±32.19)mg/L比(145.34±25.48)mg/L]水平显著高于对照组(P<0.05)。研究组住ICU时间(6.8±1.4)d和机械通气时间(1.2±0.8)d均短于对照组(7.2±1.3)d、(2.6±1.3)d,均P<0.05。研究组病人出院3个月时的神经功能缺损量表(NDS)评分[(13.32±2.87)分比(17.53±2.93)分]和美国国立卫生研究院脑卒中量表(NIHSS)评分[(12.18±2.29)分比(15.65±2.56)分]均明显低于对照组(P<0.05)。研究组出院6个月时BI明显高于对照组(69.26±8.28比54.69±7.34,P<0.05)。结论相较于常规肠内营养支持,肠内序贯营养支持更能有效维持老年重症脑卒中病人的营养状态,病人神经功能和生活质量改善更好。
Objective To analyze the effect of intestinal sequential nutritional support in elderly patients with severe stroke.Methods Eighty elderly patients with severe stroke admitted to the People's Hospital of Lixin County from June 2016 to June 2019 were randomly assigned into the control group(n=40)and the study group(n=40),and were given routine enteral nutrition support and sequential enteral nutrition support respectively.Nutritional status and neurological function were measured at admission and 14 days after treatment.Barthel index(BI)was used to evaluate the quality of life of patients 6 months after discharge.Results The levels of serum albumin(Alb)and prealbumin(PA)of the two groups of patients were significantly lower than those on admission(P<0.05)at the 14th day of treatment.The patients in the study group were treated for 14 d with serum Alb[(35.24±3.18)g/L vs.(30.16±3.52)g/L],PA[(216.17±32.19)mg/L vs.(145.34±25.48)mg/L]levels were significantly higher than those of the control group(P<0.05).The study group stayed in ICU(6.8±1.4)d and mechanical ventilation time(1.2±0.8)d were shorter than those of the control group(7.2±1.3)d,(2.6±1.3)d(P<0.05).The neurological deficit scale(NDS)score[(13.32±2.87)points vs.(17.53±2.93)points]and the National Institutes of Health Stroke Scale(NIHSS)score of the patients in the study group at 3 months after discharge from the hospital[(12.18±2.29)points vs.(15.65±2.56)points]were significantly lower than those of the control group(P<0.05).BI in the study group was significantly higher than that in the control group at 6 months after discharge[(69.26±8.28)vs.(54.69±7.34),P<0.05].Conclusion Compared with conventional enteral nutrition support,enteral sequential nutrition support is more effective in maintaining the nutritional status of elderly patients with severe stroke,and the neurological function and quality of life of the patients are better improved.
作者
庄学仕
ZHUANG Xueshi(Department of Critical Medicine,People´s Hospital of Lixin County,Bozhou,Anhui 236700,China)
出处
《安徽医药》
CAS
2023年第4期771-774,共4页
Anhui Medical and Pharmaceutical Journal