摘要
非痴呆性血管性认知障碍(VCIND)作为一种早期、轻度的认知功能障碍,如果及时发现并治疗,治愈的可能性很大,但若放任不顾,将会严重威胁患者生命健康。VCIND的发病机制复杂,西医治疗效果并不明显,根据中医学理论,其病机主要有肾精亏虚、瘀血阻滞与痰蒙清窍等。针灸作为中医不可或缺的一部分,具有多靶点、多途径的优势,可通过特殊穴位配伍以及特定的操作手法,在治疗上发挥独特优势。因此,本研究对最近的国内外研究进行总结概括,进一步探析针灸治疗VCIND的机制,完善理论依据,经研究发现针灸可能是通过减轻炎性反应、修复脑内结构、促进神经营养因子的表达、激活自噬、降低AchE活性、降低Hcy含量和改善脑循环等途径发挥治疗作用。
Vascular cognitive impairment no dementia(VCIND), as an early and slight cognitive impairment, can threaten the life of the patient without proper treatment. It is highly possible to cure VCIND with early discover and early intervention. The pathogenesis of VCIND is complex and western medicine has no significant effect on the disease. According to the theories in Chinese medicine, the pathogenesis of VCIND can be Kidney-essence deficiency, blood stasis and phlegm-dampness blocking orifices. Acupuncture and moxibustion, as an indispensable part of Chinese medicine, plays the unique role in treating VCIND by means of specific acupoints compatibility and specific manipulations with its features of multiple targets and multiple ways. This study summarized the relevant researches at home and abroad, it explored the mechanism of acupuncture and moxibustion in treating VCIND, and found that acupuncture and moxibustion might play the treating role through relieving inflammation, repairing intracerebral structure, promoting expressions of neurotrophic factors, activating autophagy, reducing AchE activity, decreasing Hcy content and improving cerebral circulation.
作者
王储
王东岩
宋晶
张虹岩
张莹
崔乃松
WANG Chu;WANG Dongyan;SONG Jing;ZHANG Hongyan;ZHANG Ying;CUI Naisong(Heilongjiang University of Chinese Medicine,Harbin 150040,China;The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,China)
出处
《针灸临床杂志》
2023年第2期98-101,共4页
Journal of Clinical Acupuncture and Moxibustion
基金
国家自然科学基金面上项目,编号:81774426
黑龙江省自然科学基金联合引导项目,编号:LH2019H113。
关键词
针灸
非痴呆性
血管性
认知障碍
机制研究
Acupuncture and moxibustion
Non-dementia type
Vascular
Cognitive impairment
Mechanism study
