摘要
目的观察麻杏石甘汤联合中药穴位贴敷治疗风热型小儿咳喘的临床效果。方法本文为前瞻性研究,选取河南省直第二人民医院2020年5月至2022年2月收治的113例咳喘患儿为研究对象。采用随机数字表将患儿分为联合组(n=57)和常规组(n=56)。常规组予以一般西医治疗;联合组在此基础上予以麻杏石甘汤联合穴位贴敷治疗。比较两组患儿治疗后的症状缓解时间,中医主证、次证积分,气道炎症反应改善情况,于治疗后开展为期6个月的短期随访,比较两组患儿肺功能改善情况。结果治疗后,联合组患儿的咳嗽、发热、喘息、肺部啰音等症状改善时间均低于常规组,咳嗽不爽、痰黄黏稠、口渴咽痛等中医主证以及发热头痛、恶风微汗等中医次证积分均低于常规组,白细胞计数(WBC)、中性粒细胞百分比(NE)、血清淀粉样蛋白A(SAA)、降钙素原(PCT)等气道炎症指标水平低于常规组,差异具有高度统计学意义(P<0.001);随访期间,联合组治疗后1、3、6个月时的第一秒用力呼气容积百分比(FEV1%)均高于常规组,差异具有高度统计学意义(P<0.001)。结论采用麻杏石甘汤联合中药穴位贴敷治疗风热型小儿咳喘的效果显著,对促进患儿症状恢复、改善中医症候体征、缓解气道炎症并改善肺功能均有积极意义。
Objective To observe the clinical effect of Maxing Shigan decoction combined with acupoint application of traditional Chinese medicine on children with cough and asthma of wind heat type.Methods This prospective study of this paper selected 113 children with cough and asthma treated in the Second People's Hospital directly under the Central Government of Henan Province from May 2020 to February 2022.The children were divided into the combined group(n=57)and the conventional group(n=56)by using the random number table.The conventional group was treated with general western medicine;On this basis,the combined group was treated with Maxing Shigan decoction combined with acupoint application.The symptom relief time,scores of main and secondary syndromes of TCM,and improvement of airway inflammation were compared between the two groups after treatment.A short-term follow-up of 6 months was carried out after treatment to compare the improvement of lung function between the two groups.Results After treatment,the improvement time of cough,fever,wheezing,lung rale and other symptoms of children in the combined group was lower than that in the conventional group.The scores of the main TCM syndromes such as cough,yellow and sticky phlegm,thirst and sore throat,as well as the scores of the secondary TCM syndromes such as fever and headache,aversion to wind and slight perspiration were lower than those in the conventional group.The levels of airway inflammation indicators such as WBC,NE,serum amyloid A,and procalcitonin(PCT)were lower than those in the conventional group,The difference was statistically significant(P<0.001);During the follow-up period,the percentage of forced expiratory volume in the first second(FEV1%)in the combined group at 1,3,and 6 months after treatment was higher than that in the conventional group,with a highly statistically significant difference(P<0.001).Conclusion Maxing Shigan decoction combined with acupoint application of traditional Chinese medicine has a significant effect on children with cough and asthma of wind heat type,which has a positive significance in promoting the recovery of symptoms,improving the symptoms and signs of traditional Chinese medicine,relieving airway inflammation and improving lung function.
作者
郭晓杰
尹焕培
GUO Xiao-jie;YIN Huan-pei
出处
《中国疗养医学》
2023年第1期100-103,共4页
Chinese Journal of Convalescent Medicine
基金
河南省医学科技攻关项目(LHGJ2021001125),基于麻杏石甘汤在治疗小儿咳喘中的作用机制研究。
关键词
风热型小儿咳喘
麻杏石甘汤
中药穴位贴敷
中医证候
症状改善
气道炎症
肺功能
Cough and asthma of wind heat type in children
Maxing Shigan decoction
Acupoint application of traditional Chinese medicine
TCM symptoms
Improved symptoms
Airway inflammation
Pulmonary function
