摘要
目的观察脐灸联合中西药治疗中老年习惯性便秘的临床疗效及对血清胃泌素(GAS)、胃动素(MTL)水平的影响。方法将100例中老年习惯性便秘患者随机分为可啶肠溶组(30例)、益气治疗组(35例)和脐灸联合组(35例)。可啶肠溶组采用口服比沙可啶肠溶片治疗,益气治疗组口服比沙可啶肠溶片联合补中益气汤治疗,脐灸联合组在益气治疗组治疗基础上联合脐灸治疗。采用放射免疫法检测血清生长抑素(SS)、GAS、MTL、P物质(SP)和一氧化氮(NO)水平,采用Wexner评分评估患者排便困难程度,统计患者排便次数,观察治疗前后症状评分变化,并比较3组临床疗效。结果与可啶肠溶组和益气治疗组比较,脐灸联合组血清SS和NO水平、Wexner评分及症状评分显著降低(P<0.05)。与可啶肠溶组和益气治疗组比较,脐灸联合组血清GAS、MTL和SP水平及排便次数显著升高(P<0.05)。脐灸联合组总有效率高于可啶肠溶组和益气治疗组(P<0.05)。结论脐灸联合中西药治疗中老年习惯性便秘可增加排便次数,缓解排便困难症状。
Objective To observe the clinical efficacy of umbilical moxibustion combined with Chinese and Western medicines in the treatment of habitual constipation in the middle-aged and elderly and its effects on the serum gastrin(GAS)and motilin(MTL)levels of patients.Method One hundred middle-aged and elderly patients with habitual constipation were randomly divided into the Bisacodyl enteric-coated group(30 cases),the Qi-supplementing treatment group(35 cases),and the combined umbilical moxibustion group(35 cases).The Bisacodyl enteric-coated group was treated with oral Bisacodyl enteric-coated tablets,the Qi-supplementing treatment group was treated with oral Bisacodyl enteric-coated tablets combined with Bu Zhong Yi Qi Tang,and the combined umbilical moxibustion group received umbilical moxibustion in addition to the treatment used in the Qi-supplementing treatment group.The serum somatostatin(SS),GAS,MTL,substance P(SP),and nitric oxide(NO)levels were measured by radioimmunoassay;the Wexner score was used to evaluate the degree of difficulty in bowel movements,and the bowel movement frequency was counted;the changes in the symptom score before and after treatment were observed,and the clinical efficacy of the three groups was compared.Result Compared with the Bisacodyl enteric-coated group and the Qi-supplementing treatment group,the serum SS and NO levels,the degree of difficulty in bowel movements,and the symptom score were significantly lower in the combined umbilical moxibustion group(P<0.05).Compared with the Bisacodyl enteric-coated group and the Qi-supplementing treatment group,the serum GAS,MTL,and SP levels and bowel movement frequency were significantly higher in the combined umbilical moxibustion group(P<0.05).The overall effective rate of the combined umbilical moxibustion group was higher than that of the Bisacodyl enteric-coated group and the Qi-supplementing treatment group(P<0.05).Conclusion Combination of umbilical moxibustion and Chinese and Western medicines can increase the bowel movement frequency and improve the difficulty in bowel movements in treating habitual constipation in the middle-aged and elderly.
作者
刘伟花
赵蓉
秦娜
曹蓉
霍萌
祁爱风
刘素芳
张艳霞
邢峰丽
白雪艳
韩培英
LIU Weihua;ZHAO Rong;QINNa;CAO Rong;HUO Meng;QI Aifeng;LIU Sufang;ZHANG Yanxia;XING Fengli;BAI Xueyan;HAN Peiying(Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang 050051,China;Hebei Provincial Hospital of Traditional Chinese Medicine,Shijiazhuang 050011,China)
出处
《上海针灸杂志》
2022年第11期1053-1058,共6页
Shanghai Journal of Acupuncture and Moxibustion
基金
河北省中医药管理局科研项目(ZL20180008)。
关键词
灸法
脐灸
便秘
胃泌素
胃动素
Moxibustion
Umbilical moxibustion
Constipation
Gastrin
Motilin
