摘要
目的通过患病率的Meta分析,系统评价我国冠心病患者经皮冠状动脉介入治疗(PCI)术后在院抑郁的患病情况。方法系统检索中国知网、万方数据库、维普网、中国生物医学文献数据库、PubMed、Cochrane数据库、Embase、Web of Science,检索时限为建库至2022年1月15日,收集有关我国冠心病患者PCI术后在院抑郁的观察性研究,并进行规范的文献质量评价,采用Stata 14.0软件进行患病率的Meta分析。结果共纳入研究11篇,包括4600例样本量,其中抑郁患者1390例,我国冠心病患者PCI术后在院抑郁患病率经Meta整合为27.6%(95%CI 22.8%~32.5%)。亚组分析显示,60岁以上患者在院抑郁患病率为31.9%(95%CI27.4%~36.4%),女性患者为28.7%(95%CI 24.8%~32.7%),小学及以下学历患者为31.2%(95%CI 24.4%~37.9%),2019年及以前患者为31.4%(95%CI 29.8%~32.9%),南方患者为29.7%(95%CI 25.2%~34.1%),使用汉密顿抑郁量表的患者为35.9%(95%CI 33.9%~37.9%),有以上因素的患者抑郁检出率较高。结论我国冠心病患者PCI术后在院抑郁患病率较高,临床医务工作者可结合相关因素对冠心病患者PCI术后情绪进行干预。
Objective The prevalence of depression in hospitalized patients with coronary heart disease after PCI was systematically evaluated by meta-analysis.Methods Literature search was systematically conducted in CNKI,Wanfang database,VIP,CBM,PubMed,Cochrane library,Embase and Web of Science.The retrieval time limit was from the establishment of the database to January 15,2022.The observational studies on post PCI depression of coronary heart disease in China were collected and the standardized literature quality was evaluated.The meta-analysis was carried out with Stata 14.0 software.Results A total of 11 studies were included,including 4600 samples and 1390 patients with depression.The prevalence of depression in Chinese patients with coronary heart disease after PCI was 27.6%(95%CI22.8%–32.5%)after meta-analysis.Subgroup analysis showed that 31.9%(95%CI 27.4%–36.4%)of patients over 60 years old,28.7%(95%CI 24.8%–32.7%)of female patients,31.2%(95%CI 24.4%-37.9%)of patients with low academic qualifications,31.4%(95%CI 29.8%-32.9%)of patients in 2019 and before,29.7%(95%CI 25.2%-34.1%)of patients in the South and 35.9%(95%CI 33.9%-37.9%)of patients using the HAMD scale had higher depression detection rates.Conclusions The prevalence of depression in patients with coronary heart disease after PCI is high in China.Clinical medical workers can intervene patients with coronary heart disease after PCI combined with relevant factors.
作者
孙春艳
韦云
胡蕾
徐南娇
SUN Chun-yan;WEI Yun;HU Lei;XU Nan-jiao(Nanjing Drum Tower Hospital Affi liated to Nanjing University Medical School,Nanjing 210008,China)
出处
《中国介入心脏病学杂志》
2022年第10期775-782,共8页
Chinese Journal of Interventional Cardiology
基金
南京大学现代医院管理与发展研究所、南京鼓楼医院医学发展医疗救助基金会资助项目(NDYG2019014、NDYG2019018、NDYG2019027、NDYG2020046)
南京大学医学院附属鼓楼医院项目(ZSA1470-1、2022-A1470)
南京鼓楼医院临床研究专项资金项目(2022-LCYJ-PY-23)。
关键词
冠心病
经皮冠状动脉介入治疗
抑郁
患病率
META分析
Coronary heart disease
Percutaneous coronary intervention
Depression
Prevalence
Meta analysis
