摘要
目的观察运肠方治疗气滞型结肠慢传输型便秘(STC)的临床疗效。方法将120例气滞型STC患者按照随机数字表法分为2组,对照组60例予琥珀酸普芦卡必利片口服,治疗组60例予运肠方口服。2组均以14 d为1个疗程,均治疗2个疗程。比较2组治疗前后临床症状评分及结肠传输试验(CTT)结果,并统计临床疗效。结果治疗组总有效率88.33%(53/60),对照组总有效率73.33%(44/60),治疗组疗效优于对照组(P<0.05)。2组治疗后各项临床症状评分均较本组治疗前降低(P<0.05),且治疗组治疗后评分均低于对照组(P<0.05)。2组治疗后CTT标记物24、48、72 h残留率均较本组治疗前同一时间节点降低(P<0.05),且治疗组治疗后CTT标记物24、48、72 h残留率均低于对照组同一时间节点(P<0.05)。结论运肠方治疗气滞型STC临床疗效确切,可有效缓解患者的临床症状,提高结肠传输能力。
Objective To study Yunchang Formula in treatment of slow transit constipation(STC)of gas stagnation.Methods Totally 120 STC patients(gas stagnation)were randomly grouped,60 cases(control group)received oral intervention of prucalopride succinate,60 cases(treatment group)received oral intervention of Yunchang Formula.The treatment continued for 2 courses(1 course for 14 days),the aim was to compare symptom score and colonic transit test(CTT);the curative effect was assessed.Results The overall effective rate in the treatment group was better than that in the control group(88.33%[53/60]vs 73.33%[44/60],[P<0.05],respectively).After treatment,the scores of clinical symptoms in groups were decreased(P<0.05),the reduction in the treatment group was more prevalent(P<0.05);the 24-h,48-h and 72-h residual rate of CTT markers in the two groups were decreased as compared to those before treatment at the same time point(P<0.05),which were decreased in the treatment group than the concurrent control group(P<0.05).Conclusion For STC patients(gas stagnation),Yunchang Formula has definite curative effect,can effectively relieve clinical symptoms and improve the capacity of colonic transit.
作者
王嘉欣
沈瑞红
邢文钰
孙立达
陈雪清
WANG Jiaxin;SHEN Ruihong;XING Wenyu;SUN Lida;CHEN Xueqing(Hebei University of Chinese Medicine,Shijiazhuang,Hebei 050091;Third Department of Anorectal,The First Affiliated Hospital of Hebei University of Chinese Medicine,Shijiazhuang,Hebei 050011)
出处
《河北中医》
2022年第8期1262-1266,共5页
Hebei Journal of Traditional Chinese Medicine
基金
河北省科学技术厅科技攻关计划项目(编号:052761638)。
关键词
便秘
气滞
中药疗法
Constipation
Gas stagnation
Traditional Chinese medicine therapy
