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衣原体在消化道定植的作用和机制进展

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摘要 衣原体不仅感染生殖道黏膜,而且能够在消化道中长期存活,对生殖道衣原体感染及致病有重要意义。衣原体质粒编码蛋白可以促进衣原体在消化道不同区域中的适应性,参与在上消化道黏膜组织的相互作用,使衣原体存活并长期定植于消化道。其中质粒编码蛋白pGP3参与衣原体耐受胃酸杀伤作用,对维持衣原体存活、定植于消化道有重要意义。探索研究质粒编码蛋白抵御胃液杀伤的耐酸机制,可为进一步研究衣原体通过消化道定植对生殖道感染及其致病性的影响奠定基础。
出处 《中华传染病杂志》 CAS CSCD 2022年第7期442-445,共4页 Chinese Journal of Infectious Diseases
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