摘要
目的:观察灸刺督脉疗法治疗气虚血瘀型缺血性脑卒中(CIS)偏瘫患者的临床疗效及其对颅内血流动力学、血清环磷酸腺苷(c AMP)、环磷酸鸟苷(cGMP)水平的影响。方法:选择109例气虚血瘀型CIS偏瘫患者,采用随机数字表法分为对照组54例和观察组55例。2组均予以基础病管理,对照组采用常规针刺治疗,观察组加用灸刺督脉疗法治疗。比较2组临床疗效及步行能力、颅内血流动力学及血清cAMP、cGMP水平变化。结果:观察组总有效率为89.09%,对照组为72.22%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组6 min行走距离及10 m行走时间均较治疗前改善(P<0.05),且观察组上述2项指标改善程度均优于对照组(P<0.05)。治疗后,2组脑前动脉流速、中动脉流速、后动脉流速均较治疗前升高(P<0.05),且观察组上述3项指标改善均优于对照组(P<0.05)。治疗后,2组cAMP、cGMP水平均较治疗前改善(P<0.05),且观察组上述2项指标改善均优于对照组(P<0.05)。结论:应用灸刺督脉疗法治疗气虚血瘀型CIS偏瘫患者疗效显著,能改善步行能力、颅内血流动力学指标及血清cAMP、cGMP水平。
Objective:To observe the clinical effect of the therapy of moxibustion and acupuncture on governor vessel for patients with cerebral ischemic stroke(CIS)of qi deficiency and blood stasis type complicated with hemiplegia and its effect on intracranial hemodynamics and serum levels of cyclic adenosine monophosphate(cAMP)and cyclic guanosine monophosphate(cGMP).Methods:A total of 109 patients with CIS of qi deficiency and blood stasis type complicated with hemiplegia were randomly divided into the control group and the observation group,with 54 and 55 cases in each group respectively.Both groups were treated with management of underlying disease,the control group was treated with routine acupuncture,and the observation group was additionally treated with the therapy of moxibustion and acupuncture on governor vessel.The clinical effects and changes of walking ability,intracranial hemodynamics and serum levels of cAMP and cGMP were compared between the two groups.Results:The total effective rate was 89.09%in the observation group and 72.22%in the control group,the difference being significant(P<0.05).After treatment,the six-minute walking distance and ten-meter walking time in the two groups were improved when compared with those before treatment(P<0.05),and the improvement of the two indexes in the observation group was better than that in the control group(P<0.05).After treatment,the flow velocity of anterior cerebral artery,middle cerebral artery and posterior cerebral artery in the two groups was increased when compared with that before treatment(P<0.05),and the improvement of the three indexes in the observation group was better than that in the control group(P<0.05).After treatment,the levels of cAMP and cGMP in the two groups were improved when compared with those before treatment(P<0.05),and the improvement of the two indexes in the observation group was better than that in the control group(P<0.05).Conclusion:The application of the therapy of moxibustion and acupuncture on governor vessel has an obvious curative effect on patients with CIS of qi deficiency and blood stasis type complicated with hemiplegia,which can improve the walking ability,intracranial hemodynamics indexes and the levels of cAMP and cGMP.
作者
王兴梅
朱东晓
WANG Xingmei;ZHU Dongxiao
出处
《新中医》
CAS
2022年第12期193-196,共4页
New Chinese Medicine
关键词
脑卒中
偏瘫
气虚血瘀
针刺疗法
灸刺督脉疗法
环磷酸腺苷、环磷酸鸟苷
Stroke
Hemiplegia
Qi deficiency and blood stasis
Acupuncture therapy
Moxibustion and acupuncture therapy
Cyclic adenosine monophosphate
Cyclic guanosine monophosphate
