摘要
目的 探讨神经内镜微创手术对高血压脑出血患者的治疗效果,及对并发症及生活质量的影响。方法方便选取2016年3月—2021年3月期间该院收治的130例高血压脑出血患者,以随机分组原则分组,观察组(n=65)以神经内镜微创手术治疗,对照组(n=65)以传统开颅手术治疗,比较两组效果。结果 观察组总有效率高于对照组(90.77%vs 69.23%),差异有统计学意义(χ^(2)=9.423,P=0.002)。观察组手术时间、术后住ICU时间、术中出血量均优于对照组,差异有统计学意义(P<0.05);术后3个月,观察组格拉斯哥预后评分(GOS)明显高于对照组,差异有统计学意义(P<0.05)。术前,两组患者认知功能(MMSE)、日常生活能力(ADL)评分对比,差异无统计学意义(P>0.05),术后3个月观察组各指标评分均高于对照组,差异有统计学意义(P<0.05)。术后观察组患者血浆内皮素(ET)、C-反应蛋白(CRP)、白介素(IL-6)水平水平均低于对照组,差异有统计学意义(P<0.05)。观察组患者并发症发生率低于对照组(6.15%vs 20.00%),差异有统计学意义(χ^(2)=5.481,P=0.019)。结论神经内镜微创手术在高血压脑出血患者中的应用价值显著,有利于提升患者日常生活能力,减少并发症发生,可推广。
Objective To investigate the therapeutic effect of neuroendoscopic minimally invasive surgery on patients with hypertensive intracerebral hemorrhage,and its impact on complications and quality of life.Methods A total of 130 patients with hypertensive intracerebral hemorrhage admitted to the hospital from March 2016 to March 2021 were conveniently selected and randomly divided into groups.The observation group(n=65)was treated with neuroendoscopic minimally invasive surgery,and the control group(n=65)was treated with traditional craniotomy.The effects of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group(90.77%vs 69.23%),the difference was statistically significant(χ^(2)=9.423,P=0.002).The operation time,postoperative ICU stay time,and intraoperative blood loss in the observation group were better than those in the control group,the difference was statistically significant(P<0.05);three months after the operation,the Glasgow Outcome Scale(GOS)of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Before operation,there was no statistically significant difference in the scores of cognitive function(MMSE)and activities of daily living(ADL)between the two groups,the difference was not statistically significant(P>0.05),and the scores of each index in the observation group were higher than those in the control group 3 months after operation,the difference was statistically significant(P<0.05).After operation,the levels of plasma endothelin (ET), C-reactive protein (CRP) and interleukin (IL-6) in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05). The incidence of complications in the observation group was lower than that in the control group (6.15% vs 20.00%),the difference was statistically significant(χ^(2)=5.481, P=0.019). Conclusion The application value of neuroendoscopic minimally invasive surgery in patients with hypertensive intracerebral hemorrhage is significant, which is conducive to improving the daily living ability of patients and reducing the occurrence of complications, and can be promoted.
作者
陈文远
陈金龙
邵合队
蒋财谋
郭之通
CHEN Wenyuan;CHEN Jinlong;SHAO Hedui;JIANG Caimou;GUO Zhitong(Department of Neurosurgery,Xiamen Third Hospital,Xiamen,Fujian Province,361100 China)
出处
《中外医疗》
2022年第13期65-69,共5页
China & Foreign Medical Treatment
关键词
神经内镜微创手术
高血压脑出血
并发症
Neuroendoscopic minimally invasive surgery
Hypertensive intracerebral hemorrhage
Complications
