摘要
目的通过分析抗青光眼手术前后睑板腺形态的变化,评估该手术与睑板腺功能障碍的关系。方法98例(107眼)行抗青光眼手术治疗患者,分别于术前1周、术后6个月采用OSDI及OCULUS眼表综合分析仪进行眼表评估。比较患者术前1周、术后6个月OSDI评分;患者手术眼、未手术眼术前1周、术后6个月睑板腺缺失程度评分。结果术后6个月,患者OSDI评分(38.84±7.62)分高于术前1周的(26.47±8.18)分,差异有统计学意义(P<0.05)。术后6个月,手术眼睑板腺缺失程度评分(2.94±0.47)分高于术前1周的(2.17±0.53)分,差异有统计学意义(P<0.05);未手术眼睑板腺缺失程度评分与术前1周比较差异无统计学意义(P>0.05)。结论抗青光眼手术术后可加重睑板腺功能障碍,需要重视围手术期眼表的管理以减少术后干眼的发生。
Objective To evaluate the correlation between morphology changes and dysfunction of meibomian gland by analyzing the morphological changes of meibomian gland before and after anti-glaucoma surgery.Methods There were 98 patients(107 eyes)who underwent anti-glaucoma surgery,and the ocular surface was evaluated by OSDI and OCULUS ocular surface integrated analyzer at 1 week and 6 months postoperatively.Comparison was made on OSDI scores at 1 week preoperatively and 6 months after surgery,the degree of meibomian gland deficiency score at 1 week preoperatively and 6 months after surgery in the operated and unoperated eyes.Results At 6 months postoperatively,the OSDI score(38.84±7.62)points was higher than(26.47±8.18)points at 1 week preoperatively,and the difference was statistically significant(P<0.05).At 6 months postoperatively,the meibomian gland deficiency score(2.94±0.47)points was higher than(2.17±0.53)points at 1 week preoperatively,and the difference was statistically significant(P<0.05);there was no statistically significant difference in meibomian gland deficiency score in the unoperated eyes compared with that at 1 week preoperatively(P>0.05).Conclusion Anti-glaucoma surgery can aggravate the dysfunction of meibomian gland,and attention should be paid to the management of the ocular surface during surgery to reduce the occurrence of postoperative dry eye.
作者
李丽娟
秦南
蔺云霞
徐玲
LI Li-juan;QIN Nan;LIN Yun-xia(Shenyang He’s Eye Hospital,Shenyang 110034,China)
出处
《中国现代药物应用》
2022年第6期44-46,共3页
Chinese Journal of Modern Drug Application
关键词
青光眼
干眼
睑板腺功能障碍
睑板腺
Glaucoma
Dry eye
Meibomian gland dysfunction
Meibomian
