摘要
目的探讨妊娠糖尿病孕妇胎儿颈部透明层厚度(NT)与妊娠结局的相关性。方法选取2018年10月至2020年10月在十堰市人民医院分娩且接受NT检查的糖尿病孕产妇294例,依据NT值分为4组:<2 mm(A组)、2~<2.5 mm(B组)、2.5~<3.5 mm(C组)、≥3.5 mm(D组)。同时在检查出妊娠糖尿病时立即进行医学营养指导,对比分析4组患者的基线资料、染色体异常情况,以及与妊娠结局的关系。结果A~D组孕产妇人数分别为206、26、30、32例;染色体异常检出率分别为4.9%、38.5%、40.0%、62.5%,D组染色体异常检出率均显著高于A、B、C组(P<0.001)。D组剖宫产、妊娠高血压综合征、羊水过多、新生儿低体重、新生儿死亡比例均高于其余3组(P<0.001)。结论妊娠糖尿病孕妇胎儿颈部透明层厚度与妊娠结局呈正相关。
Objective To explore the correlation between the fetal nuchal translucency(NT)thickness and pregnancy outcome in pregnant women with gestational diabetes mellitus(GDM).Methods A total of 294 diabetic pregnant women received the NT examination in this hospital from October 2018 to October 2020 were selected and divided into four groups according to the NT thickness:the group A(NT thickness<2 mm),group B(NT thickness 2-2.5 mm),group C(NT thickness<3.5 mm)and group D(NT thickness≥3.5 mm).At the same time,the medical nutrition guidance was given immediately after GDM was detected.Then the relationship between baseline situation,chromosomal abnormalities and pregnancy outcome among the four groups was comparatively analyzed.Results The cases number of pregnant women with GDM in the group A,B,C and D was 206,26,30 and 32 respectively.The detection rates of chromosomal abnormalities in the group A-D were 4.9%,38.5%,40.0%and 62.5%respectively.The detection rate in the group D was significantly higher than that in the group A,B and C(P<0.001).The proportions of cesarean section,pregnancy induced hypertension syndrome,excessive amniotic fluid,low birth weight and neonatal death in the group D were higher than those in the other three groups.Conclusion There is a positive correlation between the NT thickness and the pregnancy outcome in pregnant women with GDM.
作者
陈祯
高霞
赵杨
刘芳芳
张利平
CHEN Zhen;GAO Xia;ZHAO Yang;LIU Fangfang;ZHANG Liping(Department of Obstetrics,Shiyan Municipal People′ s Hospital/ Affiliated People′ s Hospital,Hubei University of Medicine,Shiyan,Hubei 442000,China;Department of Obstetrics and Gynecology,Nanchong Municipal Central Hospital,Nanchong,Sichuan 637900,China)
出处
《重庆医学》
CAS
2022年第10期1699-1702,共4页
Chongqing medicine
基金
中华国际科学交流基金会检验检测科技专项基金资助项目(Z2020LSC002)。
关键词
妊娠糖尿病
胎儿颈部透明层厚度
孕期管理
染色体异常
gestational diabetes mellitus
fetal nuchal translucency thickness
pregnancy management
chromosomal abnormalities
