摘要
目的:探索梅尼埃病(MD)患者的宽频声能吸收率特点。方法:纳入52例(52耳)单侧MD患者作为研究组,另收集30例(60耳)正常成人作为对照组,所有MD患者均行纯音测听、226 Hz声导抗、宽频声导抗测试、内耳钆造影MRI。从宽频声导抗数据库中调出峰值压力及环境压力下对应的各频率吸收率数值,选取16个频率点,将受试者按照单侧MD患者患耳与对照组、MD非症状耳与患耳2种方式分组,分别将MD患者患耳、非症状耳及对照组进行两两比较,分析其宽频声能吸收率差异。结果:MD患耳在1587~4000 Hz的吸收率显著低于对照组,差异有统计学意义(P<0.05);同一患者的患耳与非症状耳吸收率比较,差异无统计学意义;非症状耳与对照组在1587~4000 Hz的吸收率比较差异有统计学意义(P<0.05)。结论:MD患者的宽频声能吸收率于1587~4000 Hz处显著降低,具有一定的特异性表现,宽频声导抗有望作为MD诊断的参考依据之一。
Objective: To explore the wideband absorbance characteristics of patients with Meniere’s disease(MD). Methods: Wideband acoustic immittance was performed in 52 patients with unilateral Meniere’s disease(UMD) and 30 control subjects with normal hearing. All UMD patients underwent pure tone audiometry, 226 Hz acoustic immittance, wideband acoustic immittance, and gadolinium contrast MRI. Sixteen frequency points were chosen to analyze the wideband absorbance at ambient and peak pressure, and the subjects were grouped as UMD group vs. control group and asymptomatic group. The student’s t-test was used to compare the absorbance difference between them. Results: Both at peak and ambient pressure, there was a significant difference between the MD group and control group at 1587 Hz, 2000 Hz, 2519 Hz, 3174 Hz, and 4000 Hz;the MD group was lower than the control group(P<0.05);there were no differences between the asymptomatic group and the symptomatic group, there also was a significant difference between the asymptomatic group and control group at 1587-4000 Hz(P<0.05). Conclusion: The wideband absorbance in MD patients was significantly reduced within the frequency range of 1587-4000 Hz, and wideband acoustic immittance seems to be cost-effective in predicting MD.
作者
刘洁
蒋雯
林欢
李行
仝悦
刘稳
乔月华
LIUJie;JIANG Wen;LIN Huan;LI Hang;TONG Yue;LIU Wen;QIAO Yuehua(College of Medical Technology,Xuzhou Medical University,Xuzhou,221004,China;First College of Clinical Medicine,Xuzhou Medical University;Auditory Engineering Laboratory of Jiangsu Province;Department of Otolaryngology,Affiliated Hospital of Xuzhou Medical University)
出处
《临床耳鼻咽喉头颈外科杂志》
CSCD
北大核心
2021年第12期1068-1072,共5页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
梅尼埃病
宽频声导抗
宽频声能吸收率
Meniere’s disease
wideband acoustic immittance
wideband absorbance
