摘要
先天性消化道畸形是新生儿先天畸形中严重影响健康的一组常见疾病,在全球各地区发病率较高,疾病本身及术后并发症影响了患儿生活质量,并给家庭和社会带来了沉重负担。先天性消化道畸形的发生受遗传与环境等多种因素的影响,且其中环境因素占重要作用。环境因素主要包括父母年龄、母亲生活习惯、慢性疾病史、孕期药物毒物接触和不良妊娠史等。本文现对先天性消化道畸形发生的环境危险因素进行探讨和总结,以期能为疾病的预防提供帮助。
With a high global incidence,congenital digestive tract malformation(CDTM)is a common group of diseases seriously affecting neonatal health.The disease itself and its postoperative complications interfere with the quality-of-life of children and bring heavy burdens to both family and society.Numerous studies have demonstrated that the occurrence of CDTM is influenced by hereditary and environmental factors.Major environmental factors include parental age,maternal living habits,history of chronic diseases,gestational exposure to drugs or toxins and adverse pregnancy history.This review summarized the relevant environmental risk factors of CDTM to offer guidance for its prevention.
作者
刘兆州
黄金狮
杨深
李思琪
王沛则
Liu Zhaozhou;Huang Jinshi;Yang Shen;Li Siqi;Wang Peize(Department of Neonatal Surgery,Affiliated Beijing Children's Hospital,Capital Medical University,Beijing 100045,China)
出处
《中华小儿外科杂志》
CSCD
北大核心
2021年第12期1140-1144,共5页
Chinese Journal of Pediatric Surgery
关键词
胃肠道
先天性消化道畸形
环境因素
Gastrointestinal tract
Congenital digestive tract malformation
Environmental factor
