摘要
通过归纳近年来有关五味子有效成分治疗糖尿病及其并发症的文献发现,五味子主要通过改善胰岛素抵抗、抗炎、抗氧化应激、抗凋亡等机制发挥治疗糖尿病及其并发症的作用。通过对其机制总结,以期为五味子治疗糖尿病及其并发症的药效物质基础及作用机制研究提供理论依据。
By summarizing the literature on the effective ingredients of Wuweizi(Schisandrae Chinensis Fructus) in the treatment of diabetes and its complications in recent years, it is found that Wuweizi(Schisandrae Chinensis Fructus) is mainly used to treat diabetes and its complications by improving insulin resistance,anti-inflammatory, anti-oxidative stress, and anti-apoptotic mechanisms. The summary of its mechanism is expected to provide a theoretical basis for the pharmacodynamic material basis and mechanism of action of Wuweizi(Schisandrae Chinensis Fructus) in the treatment of diabetes and its complications.
作者
刘达
李丛宇
徐一方
康宁
LIU Da;LI Cong-yu;XU Yi-fang;KANG Ning(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)
出处
《中医药导报》
2021年第11期128-132,141,共6页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(81430095)。
关键词
五味子
有效成分
糖尿病
糖尿病并发症
作用机制
综述
Wuweizi(Schisandrae Chinensis Fructus)
active ingredient
diabetes
diabetic complications
complications mechanism
review
