摘要
目的探究急性复发性胰腺炎(RAP)合并代谢综合征(MS)的临床特点及预后。方法回顾性选取162例RAP患者,分为MS组43例和非MS组119例,收集并分析2组一般资料;给予2组患者保守治疗,观察其并发症及死亡情况,分析RAP合并MS患者预后不良的影响因素。结果与非MS组患者比较,MS组年龄、动脉血氧分压(PaO_(2))、血钙(Ca^(2+))显著下降,体质量指数(BMI)、糖尿病、血脂异常、高血压、Ranson评分、改良CT严重指数(MCTSI)评分、急性胰腺炎严重程度床边指数(BISAP)评分、住院时间、C-反应蛋白(CRP)显著升高,2组RAP严重程度比较差异有统计学意义(P<0.05),病因及性别之间无明显差异(P>0.05);与非MS组比较,MS组患者系统并发症以及死亡发生率升高,差异有统计学意义(P<0.05);PaO_(2)、BMI、血脂异常、糖尿病、Ranson评分、MCTSI评分、RAP严重程度是RAP合并MS患者预后不良的独立危险因素,差异有统计学意义(P<0.05)。结论RAP合并MS逐渐呈年轻化,病情较重且并发症多,对患者预后可产生不良影响。
Objective To explore the clinical characteristics and prognosis of recurrent acute pancreatitis(RAP)complicated with metabolic syndrome(MS).Methods A total of 162 patients with RAP in our hospital from February 2017 to February 2020 were selected retrospectively.According to the presence or absence of MS,patients were divided into MS group(43 cases)and non-MS group(119 cases).The general data of the two groups were collected and analyzed;Conservative treatment was given for all patients,and the complications and mortality of the two groups were observed.Factors affecting the patient's poor prognosis are analyzed in RAP patients with MS by logistic regression.Results Compared with the non-MS group,the age,partial pressure of oxygen in artery(PaO_(2)),blood calcium(Ca^(2+))were significantly decrease in MS group.Body mass index(BMI),diabetes mellitus,dyslipidemia,hypertension,Ranson score,modified CT severity index(MCTSI)score,BISAP score,length of hospital stay,C-reactive protein(CRP)in non-MS group were higher than those in MS group.There were significant differences in the etiology and severity of RAP between the two groups(P<0.05).Compared with non-MS group,the incidence of systemic complications and death were significantly increased in MS group.The PaO_(2),BMI,dyslipidemia,diabetes mellitus,Ranson score,MCTSI score and RAP severity were independent risk factors for patients with MS(P<0.05).Conclusion RAP combined with MS is gradually becoming younger,the condition is more serious,and there are many complications,which has a negative impact on the prognosis of the patient.
作者
黄莹
苗雨
林晚
刘昊
张飞雄
阮继刚
HUANG Ying;MIAO Yu;LIN Wan;LIU Hao;ZHANG Feixiong;RUAN Jigang(Gastroenterology,Cardiovascular and Cerebrovascular Disease Hospital,General Hospital of Ningxia Medical University,Yinchuan 750002,China;Affiliated Huiyi Traditional Chinese Medicine Hospital of Ningxia Medical University,Yinchuan 750004,China)
出处
《宁夏医学杂志》
CAS
2021年第11期968-971,共4页
Ningxia Medical Journal
基金
宁夏重点研发计划项目(2020BEG3001)
宁夏医科大学校级科研项目(XM2019072)。
关键词
急性复发性胰腺炎
代谢综合征
临床特点
Recurrent acute pancreatitis
Metabolic syndrome
Clinical characteristics
