摘要
目的:探讨胸部高分辨CT(HRCT)对磨玻璃结节(GGN)肺腺癌的浸润前病变、微浸润腺癌(MIA)及浸润性腺癌(IAC)的临床应用价值。方法:选取医院诊治的105例GGN肺腺癌患者,根据其浸润程度将其分为浸润前病变组(18例)、MIA组(41例)及IAC组(46例),所有患者均行胸部HRCT检查,比较HRCT对GGN肺腺癌的病理表现,分析其诊断价值。结果:HRCT表现显示浸润前病变组、MIA组及IAC组的病灶大小和CT值分别为(5.79±1.45)mm和(-542±92)HU,(7.96±2.40)mm和(-439±106)HU,(12.86±3.56)mm和(-386±91)HU,三组比较差异具有统计学意义(F=52.346,F=16.733;P<0.05)。且毛刺、分叶、胸膜凹陷征、病灶形状及边界三组组间差异均具有统计学意义(x^(2)=18.772,x^(2)=34.490,x^(2)=26.361,x^(2)=15.658,x^(2)=4.254;P<0.05),而病灶位置、空泡征及血管集束征,三组均无统计学差异(x^(2)=0.031,x^(2)=0.069,x^(2)=0.185;P>0.05)。受试者工作特征(ROC)曲线显示,定量资料病灶大小和CT值对GGN肺腺癌IAC的预测具有一定预测价值,其ROC曲线下面积(AUC)分别为0.857和0.734。结论:胸部HRCT检查磨玻璃结节样肺腺癌具有重要的诊断价值,可根据HRCT表现的定量及定性资料进行综合评估。
Objective:To investigate the clinical application value of high resolution computed tomography(HRCT)on breast in pre-invasive lesions,micro-invasive adenocarcinoma(MIA)and invasive adenocarcinoma(IAC)of lung adenocarcinoma with ground-glass nodules(GGN).Methods:105 patients with lung adenocarcinoma with GGN who were diagnosed and treated in hospital were selected as the research objects.They were divided into pre-invasive disease group(18 cases),MIA group(41 cases)and IAC group(46 cases)according to the degree of invasion.All the patients were examined with HRCT on chest.And then,the pathological manifestations of lung adenocarcinoma with GGN in HRCT among three groups were compared,and the diagnostic value of that was further analyzed.Results:The results of HRCT indicated that the lesion sizes and CT values of the pre-invasive group,MIA group and IAC group were[(5.79±1.45)mm,(-542±92)HU],[(7.96±2.40)mm,(-439±106)HU],[(12.86±3.56)mm,(-386±91)HU],the differences of them between the three groups were statistically significant(F=52.346,F=16.733,P<0.05),respectively.And the differences of burr,lobes,pleural indentation,lesion shape and boundary among three groups were statistically significant(x^(2)=18.772,x^(2)=34.490,x^(2)=26.361,x^(2)=15.658,x^(2)=4.254,P<0.05),respectively.While the differences of the location of lesion,the vacuole sign and the vessel convergence sign among three groups were no significant(x^(2)=0.031,x^(2)=0.069,x^(2)=0.185,P>0.05).The results of receiver operating characteristic(ROC)curve showed that the lesion size and CT value of quantitative data had a certain of predictive value for the IAC of lung adenocarcinoma with GGN,and the area under curves(AUC)of ROC curves of them were 0.857 and 0.734,respectively.Conclusion:HRCT examination on chest is of great diagnostic value for lung adenocarcinoma with GGN,which can comprehensively assess that according to the quantitative and qualitative data of HRCT manifestations.
作者
赵桂娟
任岩
杨冬
刘健
ZHAO Gui-juan;REN Yan;YANG Dong(Department of Radiology,Fuxin Traditional Chinese Medicine Hospital,Fuxin 123000,China)
出处
《中国医学装备》
2021年第11期60-64,共5页
China Medical Equipment
