摘要
目的探讨脑电双频指数(BIS)监测对重度子痫前期患者术后镇静治疗的指导作用。方法选取2019年10月至2020年12月江西省妇幼保健院收治的50例重度子痫前期患者作为研究对象,采用随机数字表法将其分为对照组和观察组,每组各25例。两组均接受剖宫产手术,使用硝酸甘油与地西泮注射液作为降压镇静药物。对照组采取经验性用药,观察组采取BIS监测下调节药物用量,两组术后均观察48 h。比较两组术前和术后8、24、48 h的平均动脉压(MAP)、心率(HR)水平及术后48 h子痫、产后出血及心力衰竭的发生率。结果术前两组的MAP、HR水平比较,差异无统计学意义(P>0.05);两组术后8、24、48 h的MAP、HR水平均低于术前,且术后24 h的MAP、HR水平均低于术后8 h,术后48 h的MAP、HR水平均低于术后24 h,差异有统计学意义(P<0.05),观察组术后8、24、48 h的MAP、HR水平均低于对照组,差异有统计学意义(P<0.05);观察组患者术后48 h的术后并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论BIS监测下可调控相关药物用量,进而降低重度子痫前期患者MAP、HR水平,降低患者的术后并发症发生率,指导药物达到镇静效果。
Objective To explore the guiding effect of bispectral index(BIS)monitoring on postoperative sedation treatment in patients with severe preeclampsia.Methods A total of 50 patients with severe preeclampsia treated in Maternal and Child Health Hospital of Jiangxi Province from October 2019 to December 2020 were selected as the research objects.They were divided into control group and observation group according to the random number table method,with 25 cases in each group.Both groups underwent cesarean section surgery.Nitroglycerin and Diazepam injection were used as antihypertensive sedatives.The control group took empirical medications,and the observation group took BIS to monitor the dosage of the drugs,both groups were observed for 48 hours after operation.The mean arterial pressure(MAP)and heart rate(HR)levels before operation,8,24 and 48 hours after operation,and the incidence of eclampsia,postpartum hemorrhage and heart failure at 48 hours after operation of the two groups were compared.Results There were no statistically significant differences in MAP and HR levels between the two groups before surgery(P>0.05).The MAP and HR levels of the two groups at 8,24,and 48 h after surgery were lower than those before surgery,and the MAP and HR levels at 24 h after surgery were lower than those at 8 h after surgery,and the MAP and HR levels at 48 h after surgery were lower than those at 24 h after surgery,the differences were statistically significant(P<0.05).The MAP and HR levels of the observation group at 8,24 and 48 h after surgery were lower than those of the control group,and the differences were statistically significant(P<0.05).The total incidence of postoperative complications in the observation group at 48 h after surgery was lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion BIS monitoring can regulate the dosage of relevant drugs,so as to reduce the levels of MAP and HR in patients with severe preeclampsia,reducing the incidence of postoperative complications,and guiding the drugs to achieve sedative effect.
作者
赵菲
廖宗高
龚妹
ZHAO Fei;LIAO Zong-gao;GONG Mei(Obstetrics and Gynecology Medical Intensive Care Unit,Maternal and Child Health Hospital of Jiangxi Province,Jiangxi Province,Nanchang 330006,China)
出处
《中国当代医药》
CAS
2021年第32期106-108,122,共4页
China Modern Medicine
基金
江西省卫生健康委科技计划项目(20203594)。
关键词
重度子痫前期
脑电双频指数
血压
并发症
Severe preeclampsia
Bispectral index
Blood pressure
Complication
