摘要
以常见易得且稳定的催化剂及膦配体为催化体系,进一步系统优化钯催化的无铜Sonogashira偶联制备β-(2-乙炔基苯基)环丁酮类化合物的反应体系,高产率得到一系列含有不同官能团的β-(2-乙炔基苯基)环丁酮类化合物,并进一步实现铜催化下该类化合物的开环-复分解反应.
The commonly available and stable catalysts and phosphorus ligands were used as the catalytic system,we optimized the reaction system of palladium-catalyzed copper-free Sonogashira coupling to prepareβ-(2-phenylethynyl)cyclobutanone compounds.We obtained a series of alkynyl cyclobutanone compounds with different functional groups in high yields.Furthermore,the ring-opening-metathesis of these compounds catalyzed by copper was realized.
作者
蔡润达
高继强
刘永盛
郭梓腾
王宇超
刘宇
CAI Runda;GAO Jiqiang;LIU Yongsheng;GUO Ziteng;WANG Yuchao;LIU Yu(College of Chemistry and Life Science,Changchun University of Technology,Changchun 130012,China)
出处
《吉林大学学报（理学版）》
CAS
北大核心
2021年第6期1577-1586,共10页
Journal of Jilin University:Science Edition
基金
吉林省教育厅“十三五”科学技术研究项目(批准号:JJKH20181022KJ).
