摘要
目的:探讨金芪灌洗液局部鼻腔冲洗治疗对功能性鼻内镜鼻窦术后慢性鼻-鼻窦炎患者鼻腔通气状态的影响。方法:将2019年6月至2021年3月新疆医科大学附属中医医院收治的功能性鼻内镜鼻窦术后慢性鼻-鼻窦炎患者120例采用随机数字表法分为研究组(60例)和对照组(60例)。对照组患者采用0.9%氯化钠注射液鼻腔冲洗治疗,研究组患者采用金芪灌洗液鼻腔冲洗治疗,两组患者疗程均为3个月。观察两组患者鼻气道阻力变化情况和术腔黏膜上皮化时间。结果:两组患者治疗前鼻气道阻力比较,差异无统计学意义(P>0.05);而术后第7日、术后1个月、术后2个月和术后3个月时,研究组患者鼻气道阻力明显小于对照组,差异均有统计学意义(P<0.05)。研究组患者术腔黏膜上皮化时间明显短于对照组,差异有统计学意义(P<0.01)。两组患者均未发生不良反应。结论:相较于常规0.9%氯化钠注射液鼻腔冲洗方法,采用金芪灌洗液鼻腔冲洗更有助于改善功能性鼻内镜鼻窦术后慢性鼻-鼻窦炎患者的鼻腔通气状态,且未增加不良反应。
OBJECTIVE:To probe into the effects of Jinqi lavage liquid on nasal ventilation in patients with chronic rhinosinusitis after functional endoscopic sinus surgery.METHODS:Totally 120 patients with chronic rhinosinusitis after functional endoscopic sinus surgery admitted into Affiliated Hospital of Traditional Chinese Medicine,Xinjiang Medical University from Jun.2019 to Mar.2021 were extracted to be divided into the study group(n=60)and the control group(n=60)via the random number table.The control group was treated with with 0.9%sodium chloride injection for nasal irrigation,while the study group received Jinqi lavage liquid.Both groups were treated for 3 months.Changes of nasal airway resistance and time of operative cavity epithelialization were observed.RESULTS:There was no significant difference in nasal airway resistance between two groups before treatment(P>0.05).On the 7th day,1 month,2 months and 3 months after surgery,the nasal airway resistance in the study group was significantly lower than that in the control group,with statistically significant difference(P<0.05).The time of operative cavity epithelialization in the study group was significantly shorter than that in the control group,the difference was statistically significant(P<0.01).No adverse reactions occurred in both groups of patients.CONCLUSIONS:Compared with the conventional nasal irrigation with 0.9%sodium chloride injection,Jinqi lavage liquid is more helpful to the improvement of nasal ventilation status in patients with chronic rhinosinusitis after functional endoscopic sinus surgery,and does not increase the incidence of adverse drug reactions.
作者
张伟
盛国强
龚建齐
铁玲
邹广华
李志钢
ZHANG Wei;SHENG Guoqiang;GONG Jianqi;TIE Ling;ZOU Guanghua;LI Zhigang(Dept.of Otolaryngology,Affiliated Hospital of Traditional Chinese Medicine,Xinjiang Medical University,Xinjiang Urumqi 830000,China)
出处
《中国医院用药评价与分析》
2021年第10期1173-1175,1179,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
新疆自治区卫生健康青年医学科技人才专项科研项目(No.WJWY-201959)
新疆维吾尔自治区自然科学基金项目(No.2019D01C171)。
