摘要
目的探讨硬膜外麻醉复合全麻对胸外科手术患者早期恢复及免疫功能的影响。方法选取2018年1月-2020年1月在我院收治治疗的74例需行胸外科手术的患者为研究对象,按入院的先后顺序分为对照组与观察组各37例。对照组采用全身静脉麻醉,观察组采用硬膜外麻醉符合全身静脉麻醉。在手术结束后,分别观察比较两组患者麻醉恢复情况、免疫功能指标情况。结果观察组自主呼吸恢复时间、自主睁眼时间、拔除气管插管时间均短于对照组,有统计学意义,(P<0.05)。且观察组术后48h后白介素-6(IL-6)、C反应蛋白(CRP)、皮质醇(Cor)水平优于对照组,有统计学意义(P<0.05)。结论对胸外科手术患者实施硬膜外麻醉复合全麻可抑制早期炎性反应,减轻感染的发生风险,缩短患者术后恢复时间,效果显著,值得临床应用。
Objective To investigate the effect of epidural anesthesia combined with general anesthesia on early recovery and immune function of patients undergoing thoracic surgery.Methods A total of 74 patients requiring thoracic surgery who were admitted to our hospital from January 2018 to January 2020 were selected as the study subjects.According to the order of admission, 37 patients were divided into the control group and the observation group.The control group received general intravenous anesthesia, and the observation group received epidural anesthesia consistent with general intravenous anesthesia.After the operation, the anesthesia recovery and immune function indexes of the two groups were observed and compared.Results During the observation group, the recovery time of spontaneous respiration, the time of opening eyes and the time of extubation were shorter than those of the control group(P<0.05).The levels of interleukin-6(IL-6),C-reactive protein(CRP)and cortisol(Cor)were better than those of the control group after 48 h(P<0.05).Conclusion Epidural anesthesia combined with general anesthesia can inhibit the early inflammatory response, reduce the risk of infection, and shorten the postoperative recovery time in patients undergoing thoracic surgery.
作者
陈美云
Chen Meiyun(Tongxu County Hospital Kaifeng,Henan 475000)
出处
《辽宁医学杂志》
2021年第5期87-89,共3页
Medical Journal of Liaoning
关键词
硬膜外麻醉复合全麻
胸外科
早期恢复
免疫功能
自主睁眼时间
C反应蛋白
Epidural anesthesia combined with general anesthesia
Thoracic surgery
Early recovery
Immune function
Voluntary eye opening time
C-reactive protein
