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胸腔镜肺癌根治术治疗老年非小细胞肺癌的临床疗效及安全性 被引量:4

Clinical efficacy and safety of thoracoscopic radical resection of lung cancer in elderly patients with non-small cell lung cancer
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摘要 目的针对老年非小细胞肺癌患者行胸腔镜肺癌根治术治疗,评估其疗效及安全性。方法选取2018年5月至2020年5月江西省九江市第一人民医院收治的老年非小细胞肺癌患者60例,采用随机信封编号分组,根据单双数分为观察组与对照组,每组各30例,对照组采用传统开胸手术,观察组采用胸腔镜肺癌根治术,比较两组患者的手术指标、术前、术后CRP指标变化情况及术后并发症发生率。结果观察组手术时间、拔管时间及住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05);两组清扫淋巴结数目比较,差异无统计学意义(P>0.05);两组患者术前CRP指标比较,差异无统计学意义(P>0.05),两组术后1 d、3 d、5 d CRP均升高,但组间比较观察组CRP低于对照组,差异有统计学意义(P<0.05);观察组与对照组并发症总发生率分别为6.66%、26.67%,观察组低于对照组(P<0.05)。结论胸腔镜肺癌根治术应用于老年非小细胞肺癌,在减轻手术创伤、减少炎症刺激方面有着突出效果,并发症少,安全可靠,可予以推广。 Objective To evaluate the efficacy and safety of thoracoscopic radical resection of lung cancer for elderly patients with non-small cell lung cancer(NSCLC).Methods The subjects were 60 elderly patients with non-small cell lung cancer who were admitted to Jiujiang NO.1 People's Hospital of Jiangxi Province from May 2018 to May 2020.They were divided into the observation group and the control group with 30 patients in each group according to the odd and even number of envelopes numbered randomly.The control group was given traditional thoracotomy than control group,and the observation group was given thoracoscopic radical resection of lung cancer.The surgical indicators,the changes of CRP indicators before and after surgery and the incidences of postoperative complications were compared between the two groups.Results The durations of operation,extubation and hospitalization were shorter in the observation group,and the amount of intraoperative blood loss in the observation group was less than that in the control group,with statistically significant differences(P<0.05).No significant difference was observed in the number of dissected lymph nodes between the two groups(P>0.05).No significant difference was observed in the preoperative CRP after 1 d,3 d,5 d indicators between the two groups(P>0.05).The CRP indicators in both groups were increased after the operation,but the CRP indicator in the observation group was lower than the control group(P<0.05).The total incidences of complications of the observation group and control group were 6.66%vs.26.67%,and that in the observation group was lower than that in the control group(P<0.05).Conclusion Thoracoscopic radical resection of lung cancer in the elderly non-small cell lung cancer has an outstanding effect in reducing surgical trauma and inflammatory stimulation,with fewer complications,which is safe and reliable and can be popularized.
作者 夏少锋 XIA Shaofeng(Department of Thoracic Surgery,Jiujiang NO.1 People's Hospital in Jiangxi Province,Jiujiang 332000,China)
出处 《中国现代医生》 2021年第23期48-51,共4页 China Modern Doctor
基金 江西省卫生健康委科技计划项目(202140328)。
关键词 胸腔镜 肺癌根治术 非小细胞肺癌 CRP指标 淋巴结清扫数目 并发症 Thoracoscope Radical resection of lung cancer Non-small cell lung cancer CRP indicator Number of dissected lymph nodes Complication
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