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老年餐后低血压对预后影响的前瞻性队列研究 被引量:3

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摘要 目的前瞻性研究餐后低血压(PPH)对60岁及以上患者远期预后的影响。方法连续入选2011年5月1日至2012年4月30日在中国人民解放军联勤保障部队第九二四医院干部病房住院的老年患者共133例,经测量血压后分为PPH组和非PPH(NPPH)组,随访7年。采用Kaplan-Meier法、Log-Rank检验及Cox回归模型进行预后危险因素分析。结果以全因死亡为结局,PPH患者第1、3、5、7年的累积生存率分别为96.6%、83.0%、65.9%、54.5%,低于NPPH组的100.0%、91.1%、84.4%、82.1%,两组生存时间差异有统计学意义(P<0.05)。以发生终点事件为结局,两组总生存期差异无统计学意义(P>0.05)。Cox回归结果显示,PPH、年龄、左室射血分数(LVEF)是全因死亡的独立预测因子(P<0.05),餐后收缩压下降值与全因死亡密切相关,尤其是早餐后收缩压每下降20 mmHg,死亡风险增加0.852倍(RR:1.852,95%CI:1.289~2.660)。结论老年PPH患者远期预后较NPPH患者差,全因死亡率随着早餐后收缩压下降幅度的增加而增加。
出处 《中国老年学杂志》 CAS 北大核心 2021年第16期3393-3396,共4页 Chinese Journal of Gerontology
基金 军队保健专项科研课题(12BJE14)。
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