摘要
采用脱乙酰度≥95%的壳聚糖为原料,通过NaNO_(2)氧化法降解得到不同分子量的壳聚糖。通过单因素试验,考察不同反应条件对海藻酸钠/壳聚糖/海藻酸钙微胶囊机械强度的影响,再通过响应面试验优化微胶囊的制备工艺。研究结果表明,当成膜时间为32 min,壳聚糖浓度为6.1 g/L,壳聚糖分子量为58189,壳聚糖pH值为6.0时,海藻酸钠/壳聚糖/海藻酸钙微胶囊的机械强度最高。
Chitosan with deacetylation degree≥95%was used as raw material,and chitosan with different molecular weight was degraded by NaNO_(2) oxidation.The effects of different reaction conditions on the mechanical strength of sodium alginate/chitosan/calcium alginate microcapsules were investigated by single factor test,and the preparation process of microcapsules was optimized by response surface methodology.The results showed that the mechanical strength of sodium alginate/chitosan/calcium alginate microcapsules was the highest when the formation time was 32 min,the concentration of chitosan was 6.1 g/L,the molecular weight of chitosan was 58189,and pH value of chitosan was 6.0.
作者
袁庆兰
李锐扬
宋欢
王艳
李琛
YUAN Qing-lan;LI Rui-yang;SONG Huan;WANG Yan;LI Chen(School of Chemistry,Biology and Environment,Yuxi Normal University,Yunnan Yuxi 653100;School of Mechanics and Transportation,Southwest Forestry University,Yunnan Kunming 650224,China)
出处
《广州化工》
CAS
2021年第14期55-58,共4页
GuangZhou Chemical Industry
基金
云南省科技厅科技计划项目(2018FD091)
玉溪师范学院大学生创新创业训练计划项目(2019A29)
云南省高校特色植物化学评价及应用科技创新团队支持计划。
关键词
壳聚糖
海藻酸钠
降解
微胶囊
机械强度
chitosan
sodium alginate
degradation
microcapsules
mechanical strength
