摘要
目的:探讨先兆早产孕妇自发性早产发生的影响因素。方法:回顾性分析广州市增城区人民医院2016年1月~2020年12月收治的86例先兆早产孕妇临床资料,统计自发性早产发生情况,并统计孕妇基线资料,分析先兆早产孕妇发生自发性早产的影响因素。结果:86例先兆性早产孕妇中,发生自发性早产42例(纳入发生组,其余未发生自发性早产的44例孕妇纳入未发生组),发生率为48.84%;发生组羊水过多、胎膜早破、妊娠期糖尿病、宫颈管长度≤2.5 cm、胎儿纤维连接蛋白(f FN)≥50 ng/ml占比较未发生组高,差异有统计学意义(P<0.05);Logistic回归分析结果显示,羊水过多、胎膜早破、妊娠期糖尿病、宫颈管长度≤2.5cm、f FN≥50 ng/ml可能是先兆早产孕妇发生自发性早产的影响因素(OR>1,P<0.05)。结论:先兆早产孕妇发生自发性早产与羊水过多、胎膜早破、妊娠期糖尿病、宫颈管长度≤2.5 cm、f FN≥50 ng/ml密切相关。
Objective: To investigate the influence factors of the occurrence of spontaneous preterm birth in pregnant women with threatened preterm delivery. Methods: We retrospectively collected the clinical data of 86 pregnant women with threatened preterm delivery who were admitted to Guangzhou Zengcheng District People’s Hospital from January 2016 to December 2020, counted the occurrence of spontaneous preterm birth, and counted the baseline data of pregnant women, and analyzed the influence factors of spontaneous preterm birth in pregnant women with threatened preterm delivery. Results: Among 86 pregnant women with threatened preterm delivery, 42 cases of spontaneous preterm birth occurred in 48.84% of the pregnant women who were included in the occurrence group, and the remaining 44 pregnant women who did not develop spontaneous preterm birth were included in the non occurrence group.The incidence of polyhydramnios, premature rupture of membranes, gestational diabetes mellitus, cervical length ≤2.5 cm, and fetal fibronectin(f FN)≥50 ng/ml of the occurrence group accounted for the higher proportion than that in the non occurrence group, with statistical significance(P<0.05);Logistic regression analysis showed that polyhydramnios, premature rupture of membranes, gestational diabetes mellitus, cervical length≤2.5 cm, and f FN≥50 ng/ml may be the influence factors of spontaneous preterm delivery(OR>1, P<0.05). Conclusion: The occurrence of spontaneous preterm birth in pregnant women with threatened preterm delivery is strongly associated with polyhydramnios, premature rupture of membranes, gestational diabetes mellitus, cervical length ≤2.5 cm, and f FN≥50 ng/ml.
作者
周杨
曾瑞珍
刘晓丽
吴满婷
ZHOU Yang;ZENG Rui-zhen;LIU Xiao-li;WU Man-ting(The Department of Obstetrics and Gynecology,People's Hospital of Zengcheng District,Guangzhou511300)
出处
《实用中西医结合临床》
2021年第10期126-127,131,共3页
Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词
先兆早产
自发性早产
LOGISTIC回归分析
羊水过多
胎膜早破
Threatened preterm delivery
Spontaneous preterm birth
Logistic regression analysis
Polyhydramnios
Premature rupture of membranes
