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米非司酮、米索前列醇片联合水囊引产术的临床观察 被引量:2

Clinical observation of mifepristone and Misoprostol combined with water bag induced of labour
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摘要 目的:探讨应用米非司酮、米索前列醇片联合水囊引产在妊娠10~14周引产时的临床效果。方法:回顾性分析2018年6月~2019年8月要求引产的116例妊娠患者,按随机分配原则将其分为试验组(58例)与对照组(58例)。试验组为口服米非司酮、米索前列醇片联合水囊引产术,对照组为单纯的口服米非司酮及米索前列醇片。观察两组患者口服米索前列醇片后宫缩开始时间、胎儿、胎盘流出时间、出血量;两组胎盘残留率、清宫率及成功率。结果:口服米索前列醇片后胎儿流出时间及出血量均低于对照组,两组比较差异有统计学意义(P<0.05);试验组引产成功率、术后清宫率及胎盘残留率低于对照组,进行统计学分析,差异均无统计学意义(P>0.05)。结论:联合水囊引产术的引产效果优于单纯口服米非司酮及米索前列醇片。 Objective To investigate the clinical effect of mifepristone,Misoprostol combined with water bag for induction of labor at 10~14 weeks of gestation.Method A retrospective analysis to the clinical material of 116 cases of patients accepted labor induction during June 2018 to August 2019.According to the principle of random distribution,they were divided into experimental group(58 cases)and control group(58 cases).In the experimental group,oral mifepristone,misoprostol combined with water bag induced labour,the control group was oral mifepristone and Misoprostol.The start time of uterine contraction,fetal and placental outflow time,uterine bleeding volume of oral misoprostol;Placental residual rate,uterine clearance rate and success rate in two groups.Results After oral Misoprostol,the fetal outflow time and uterine bleeding volume loss were both lower than those of the control group,the difference was statistically significant(P<0.05).The success rate of induction,postoperative uterine clearance and placental residue in the experimental group were lower than those in the control group,perform statistical analysis,there was no significant difference(P>0.05).Conclusion The combined labor induction with water bag induced of labor was better than simple oral mifepristone and Misoprostol.
作者 梁雨 LIANG Yu(Institute of Population Life Science and Technology of Jilin,Changchun 130000,China)
出处 《吉林医学》 CAS 2021年第6期1367-1369,共3页 Jilin Medical Journal
关键词 米非司酮 米索前列醇片 水囊引产 Mifepristone Misoprostol Water bag induced of labour
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