摘要
目的分析不同剂量罗哌卡因在临床麻醉及疼痛治疗中的临床效果及安全性。方法选取2018年6月至2020年6月北京市房山区中医医院实施硬膜镇痛手术的110例患者为研究对象,按照随机数字表法分成对照组和试验组,每组55例。对照组使用0.25%罗哌卡因麻醉,试验组使用0.20%罗哌卡因麻醉。观察两组患者不同时间段生命体征、疼痛评分以及麻醉实施效果、不良反应发生率。结果在麻醉后40 min试验组患者心率、平均动脉压、脉搏氧饱和度指标均低于对照组(P<0.05),但麻醉5 h后其上述指标与对照组对比,差异无统计学意义(P>0.05);且两组患者麻醉实施效果比较差异也无统计学意义(P>0.05)。试验组术后不同时间段视觉疼痛模拟评分(VAS)均低于对照组(P<0.05)。试验组术后不良反应发生率为1.82%低于对照组10.91%,差异有统计学意义(P<0.05)。结论临床麻醉及疼痛治疗中使用0.20%罗哌卡因作用效果突出,可以维持手术期间患者各项生命体征的稳定性,促进患者术后恢复,减少术后疼痛和不良反应。
Objective To analyze the clinical effect and safety of different doses of ropivacaine in clinical anesthesia and pain treatment.Methods A total of 110 patients with epidural analgesia in Fangshan District Hospital of Traditional Chinese Medicine from June 2018 to June 2020 were selected and randomly divided into control group and experimental group,with 55 cases in each group.The control group was anesthetized with 0.25%ropivacaine,and the experimental group was anesthetized with 0.20%ropivacaine.The vital signs,pain scores,anesthesia effect and the incidence of adverse reactions were observed in 2 groups at different time periods.Results The indexes of heart rate,mean arterial pressure and pulse oxygen saturation in the experimental group were lower than those in the control group at 40 minutes after anesthesia(P<0.05),but after 5 h of anesthesia,the difference of above indexes between 2 groups was not statistically significant(P>0.05);and there was no significant difference in the effect of anesthesia between the 2 groups(P>0.05).The visual analogue scale(VAS)of the experimental group was lower than that of the control group at different time points(P<0.05).The incidence of adverse reactions in the experimental group was 1.82%,which was lower than that in the control group 10.91%(P<0.05).Conclusion The effect of 0.20%ropivacaine in clinical anesthesia and pain treatment is outstanding,which can maintain the stability of vital signs during operation,promote postoperative recovery,reduce postoperative pain and adverse reactions.
作者
胡玉红
黄建军
HU Yuhong;HUANG Jianjun(Fangshan District Hospital of Traditional Chinese Medicine,Beijing 102400,China;The First Hospital of Fangshan District,Beijing 102499,China)
出处
《大医生》
2020年第23期110-112,共3页
Doctor
