摘要
5-羟甲基糠醛(5-HMF)是中药中广泛存在的化学成分,在中药炮制、贮藏、配伍过程中含量变化明显。现代药理学研究表明5-HMF具有抗氧化、改善学习记忆、抗过敏、保护神经细胞、抗炎等药理作用。结合国内外有关文献,对5-HMF在中药道地性、炮制加工、贮藏方面的含量变化及药理作用进行综述,以期为提升中药材质量标准和临床合理用药提供参考。
5-Hydroxymethyl furfural(5-HMF) is a relatively wide range of chemical constituents in traditional Chinese medicine. Its content changes significantly during the processing, storage, and compatibility of traditional Chinese medicine. Modern pharmacological studies have shown that 5-HMF has anti-oxidation, improve learning and memory, anti-allergy, protect nerve cells,anti-infla matory and other pharmacological effects. This article summarizes the content changes and pharmacological effects of5-HMF in the authenticity, processing andstorage of traditional Chinese medicine in combination with relevant literatureathome and abroad, in order to provide a reference for improving the quality standards of traditional Chinese medicine and clinical rational use of medicine.
作者
王梅
王越欣
武英茹
李宁
冯敏
张文智
荆然
郝旭亮
倪艳
WANG Mei;WANG Yuexin;WU Yingru;LI Ning;FENG Min;ZHANG Wenzhi;JING Ran;HAO Xuliang;NI Yan(Shanxi University of Traditional Chinese Medicine,Taiyuan 030619,China;Shanxi Academy of Chinese Medicine,Taiyuan 030012,China;Affiliated Hospital of Shanxi University of Chinese Medicine,Taiyuan 030024,China)
出处
《药物评价研究》
CAS
2020年第11期2319-2327,共9页
Drug Evaluation Research
基金
山西省中医药中老年健康产业技术创新联盟项目(JKCY201904)
2020年度山西省研究生教育创新项目(2020SY460)
山西省中医药研究院院级课题(201905)
山西中医药大学学科建设项目(1008Z4)
2020年山西中医药大学校级研究生创新项目(2020CX039)。
关键词
5-羟甲基糠醛
中药炮制
含量变化
药理作用
5-hydroxymethyl furfural(5-HMF)
processing of traditional Chinese medicine
content change
pharmacological effects
