摘要
慢性鼻窦炎(chronic rhinosinusitis,CRS)是鼻腔鼻窦慢性炎性疾病,属于常见的上呼吸道疾病之一。根据欧洲EPOS 2012[1],CRS定义为鼻腔和鼻窦持续超过12周的慢性炎症,其主要特征为鼻塞、流涕、伴发面部疼痛和肿胀,或是嗅觉的下降和丧失。据有关统计数据表明,全球范围内CRS的发病率日趋上升,其中欧洲和美国的发病率分别高达11%和12%[2-3],一项以国际标准化问卷进行访谈的多中心研究显示,我国的CRS发病率为8%[4]。
Chronic rhinosinusitis(CRS)is one of the common upper airway disease,which is complex and heterogenerous.It is known that based on clinical observations,CRS phenotype has been classified into CRSwNP and CRSsNP.However,there is still not any uniform standard to differentiate CRS endotype.According to CRS phenotype.The clinical effect of CRS treatment is not satisfied,including bad effects an high reccurence rate because of unclear mechanism.Therefore,it is important to explore CRS endotype,which could help us to recognize the pathologicalmechanism of the disease and to obtain optimal therapies,in order to improve health quality and relieve social burdern.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2020年第11期1049-1052,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
慢性鼻窦炎
内在型
治疗
chronic rhinosinusitis
endotype
therapy
