摘要
当归补血汤出自金代名医李东垣的《内外伤辨惑论》,由黄芪和当归5∶1配伍而成,是补气生血的经典名方,现代临床主要用于治疗贫血、调节免疫功能、保护心脑血管系统、抗肿瘤等。本文查阅中外文献,通过基于传统植物化学分离分析、药物代谢、谱效关系、生物活性筛选/化学在线分析技术、化学敲除法和网络药理学等方法,对DBD药效物质基础的研究予以总结和分析,为当归补血汤的进一步研究及应用提供科学依据。
Danggui Buxue Decoction is recorded in The Theories of Differentiation on Endogenous by Dong-yuan Li in Jin Dynasty.It consists of Astragali Radix and Angelicae Sinensis Radix with a weight ratio of 5︰1,which is a classic Chinese medicinal prescription for benefiting qi and nourishing blood.Clinically,it is mainly used in treating anemia,regulating immune function,protecting cardiovascular and cerebrovascular system,anti-tumor and so on.This paper summarizes and analyzes the research on the material basis of Danggui Buxue Decoction by referring to the Chinese and foreign literatures,so as to provide reference for the further research and application of Danggui Buxue Decoction.
作者
胡静
李科
李爱平
刘月涛
秦雪梅
HU Jing;LI Ke;LI Ai-ping;LIU Yue-tao;QIN Xue-mei(Modern Research Center for Traditional Chinese Medicine,Shanxi University,Taiyuan 030006,China;Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province,Taiyuan 030006,China)
出处
《中草药》
CAS
CSCD
北大核心
2020年第21期5658-5663,共6页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(31770362)。
关键词
当归补血汤
物质基础
化学成分
药理作用
黄芪
当归
Danggui Buxue Decoction
material basis
chemical composition
pharmacological action
Astragali Radix
Angelica Sinensis Radix
