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复方大承气汤联合腹部按摩对肠梗阻患者胃肠功能及肠黏膜通透性的影响 被引量:5

Influence of Compound Dachengqi Decoction Combined with Abdominal Massage on Gastrointestinal Function and Intestinal Mucosa Permeability in Patients with Intestinal Obstruction
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摘要 目的探讨复方大承气汤联合腹部按摩对肠梗阻患者胃肠功能及肠黏膜通透性的影响。方法采用随机数字表法将68例肠梗阻患者分为研究组和对照组,各34例。2组均接受常规治疗,研究组增加复方大承气汤联合腹部按摩,2组均连续治疗14 d。比较2组临床疗效、中医证候积分、临床相关指标及肠黏膜通透性。结果治疗后研究组总有效率高于对照组(P<0.01)。治疗后2组腹胀腹痛、恶心呕吐、大便干结的中医证候积分均明显低于治疗前,且研究组明显低于对照组(P<0.01)。与对照组比较,研究组治疗后肠蠕动恢复时间、肛门排气及腹胀/腹痛消失时间均提前,住院时间缩短(P<0.05或P<0.01)。治疗后2组血清PCT、ET水平均明显低于治疗前,且研究组明显低于对照组(P<0.01)。结论复方大承气汤联合腹部按摩更有利于肠梗阻患者肠道功能的恢复,修复受损的肠黏膜通透性,改善患者预后。 Objective To study the influence of compound Dachengqi decoction combined with abdominal massage on gastrointestinal function and intestinal mucosa permeability in patients with intestinal obstruction. Methods 68 patients with intestinal obstruction were divided into the study group and the control group according to the random number table method,with 34 cases in each group. Patients in both groups were given conventional treatment,the study group added compound Dachengqi decoction and abdominal massage. Both groups were treated continuously for 14 days. The clinical efficacy,TCM syndrome scores,clinically relevant indicators and intestinal mucosa permeability between the two groups were compared. Results The total effective rate after treatment of the study group was significantly higher than the control group( P < 0. 01). The TCM syndrome scores of abdominal distension,abdominal pain,nausea and vomiting,and dry stool after treatment in the two groups were significantly lower than before treatment,and the study group was significantly lower than the control group( P < 0. 01). Compared with the control group,the recovery time of intestinal motility,anal exhaust time and the time of disappearance of abdominal distension/abdominal pain after treatment significantly moved up,the length of hospital stay significantly shorter( P < 0. 05 or P < 0. 01). The levels of serum PCT and ET after treatment in the two groups were significantly lower than before treatment,and the study group was significantly lower than the control group( P < 0. 01). Conclusion Compound Dachengqi decoction combined with abdominal massage is more conducive to the recovery of intestinal function in patients with intestinal obstruction,repair the permeability of damaged intestinal mucosa,and improve the prognosis of patients.
作者 王润娥 胡艳萍 雒建瑞 WANG Run'e;HU Yanping;LUO Jianrui(Department of General Surgery,Lishi District People's Hospital,Shanxi Province,Lyuliang 033000,China;Department of Traditional Chinese Medicine,Lishi District People's Hospital,Shanxi Province,Lyuliang 033000,China)
出处 《光明中医》 2020年第22期3565-3567,共3页 GUANGMING JOURNAL OF CHINESE MEDICINE
关键词 肠梗阻 复方大承气汤 腹部按摩 胃肠功能 肠黏膜通透性 中医综合疗法 intestinal obstruction compound Dachengqi decoction abdominal massage gastrointestinal function intestinal mucosa permeability comprehensive therapy of TCM
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