摘要
目的通过对比分析导管接触性溶栓(CDT)与AngioJet机械吸栓术在急性下肢深静脉血栓形成的治疗效果。方法回顾性分析2018-01~2019-11安徽医科大学第二附属医院血管外科收治的34例经介入手术治疗的急性下肢深静脉血栓形成患者的临床资料,其中18例行CDT治疗(CDT组),16例行AngioJet机械吸栓治疗(AngioJet组)。比较两组患者手术前后D-二聚体(D-D)峰值及纤维蛋白原值、术后下肢消肿率及血栓清除率。结果34例患者均顺利完成手术。CDT组即刻血栓清除率、消肿率均低于AngioJet组,差异有统计学意义(P<0.05)。术后CDT组的D-D峰值及尿激酶用量均高于AngioJet组,差异有统计学意义(P<0.05)。结论AngioJet机械吸栓装置在急性下肢深静脉血栓形成治疗中具有更高的血栓清除率及安全性,对指导临床应用有一定的意义。
Objective To compare the therapeutic effects of catheter-directed thrombolysis(CDT)and AngioJet Device in acute deep venous thrombosis of lower extremity.Methods The clinical data of 34 patients with acute deep venous thrombosis of lower extremity treated with interventional surgery in the Department of Vascular Surgery of the Second Affiliated Hospital of Anhui Medical University from January 2018 to November 2019 were retrospectively analyzed,among whom 18 cases received CDT treatment(CDT group)and 16 cases received AngioJet Device treatment(AngioJet group).The preoperative and postoperative D-dimer(D-D)values and fibrinogen(Fib)values,the postoperative thrombus removal rate and lower extremity detumescence rate were compared between the patients in the two groups.Results All the 34 patients completed the operation successfully.The postoperative immediate thrombus removal rate and the detumescence rate in the CDT group were lower than those in the AngioJet group,and the differences were significant between the two groups(P<0.05).The postoperative peak value of D-D and the dosage of urokinase in the CDT group were higher than those in the AngioJet group,and the differences were significant between the two groups(P<0.05).Conclusion AngioJet Device has higher thrombus removal rate and safety in the treatment of acute deep venous thrombosis of lower extremity,which has certain significance to guide clinical application.
作者
刘月球
万圣云
LIU Yue-qiu;WAN Sheng-yun(Department of Vascular Surgery, the Second Affiliated Hospital of Anhui Medical University, Hefei 230000, China)
出处
《中国临床新医学》
2020年第11期1133-1137,共5页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
