摘要
目的:探讨分级管理对乳腺癌化疗后胃肠道反应的预防效果。方法:将2018年6月至2019年12月收治的90例乳腺癌化疗患者随机分为观察组和对照组各45例,对照组给予化疗所致恶心呕吐(CINV)常规防治方案,观察组给予CINV分级管理,比较2组患者化疗后恶心呕吐发生率和严重程度。结果:2组使用低度致吐药物患者的恶心、呕吐发生率比较差异无统计学意义(P>0.05),观察组使用中度致吐药物、高度致吐药物患者的恶心、呕吐发生率显著低于对照组(P<0.05);观察组患者恶心、呕吐症状以I级为主,观察组恶心呕吐症状严重程度明显轻于对照组(P<0.05)。结论:CINV分级管理可有效减少乳腺癌化疗所致恶心呕吐的发生,并减轻严重程度。
[Objective]To investigate the preventive effect of graded management on gastrointestinal reactions after chemotherapy in breast cancer.[Method]A total of 90 patients with breast cancer receiving chemotherapy from June 2018 to December 2019 were randomly divided into observation group(45 cases)and control group(45 cases).The control group was given the routine prevention and treatment of CINV,and the observation group was given the graded management of CINV.The incidence and severity of nausea and vomiting after chemotherapy were compared between the two groups.[Result]There was no statistically significant difference in the incidence of nausea and vomiting between the two groups(P>0.05).The incidence of nausea and vomiting in the observation group was significantly lower than that in the control group(P<0.05).The nausea and vomiting symptoms in the observation group were mainly grade I,the severity of nausea and vomiting in the observation group was significantly lower than that in the control group(P<0.05).[Conclusion]CINV graded management has a better effect on preventing gastrointestinal reactions caused by chemotherapy in breast cancer,which can effectively reduce the occurrence of nausea and vomiting and reduce the severity.
作者
沈英
郑叶平
沈丽莉
宋美芬
SHEN Ying;ZHENG Yeping;SHEN Lili;SONG Meifen(the Second Hospital of Jiaxing,Zhejiang 314000,China)
出处
《浙江医学教育》
2020年第6期35-37,51,共4页
Zhejiang Medical Education
基金
嘉兴市2019-2021年周期中医药重点学科建设计划资助(编号:2019XK-A07)。
关键词
乳腺癌
化疗
胃肠道反应
分级管理
breast cancer
chemotherapy
gastrointestinal reaction
graded management
