摘要
颌面骨缺损的再生修复是外科临床亟待解决的问题,目前主要采用的方法有自体移植、异体移植以及人工合成替代物修补的方法。3D打印技术凭借其快速成型、设计精准、个性化等优点,在替代物制造与加工、治疗方案设计与预演、术前指导等方面发挥着重要的作用。通过采用不同材料、不同制造技术获得具有良好机械性能和生物相容性的模具、种植体、移植物,可以进行骨骼和软组织的修补及诱导再生。随着3D打印技术的日益发展,可选择的生物材料种类越来越多,组织工程支架的研究也成为研发的热点。本文就近年来国内外应用于颌面部骨缺损的3D打印材料的研究及发展状况进行总结,并展望3D打印技术的发展前景。
Maxillofacial bone defect reconstruction remains a critical challenge in clinical surgery.With the advantages of rapid prototyping,accurate design and personalisation,3D printing technology plays an important role in the manufacturing,processing,treatment program design rehearsal and preoperative fabrication of substitutes.Bone replacement with good mechanical properties and biocompatibility could be acquired using different materials and manufacturing techniques for maxillofacial reconstruction.3D printing technology allows the use of additional biological materials and promotes the scaffolding preparation for tissue-engineered bones.In this paper,the current research and development of 3D printing materials applied in maxillofacial bone defects at home and abroad were summarised,and the developing trend of 3D printing technology was prospected.
作者
张心驰
吴炜
Zhang Xinchi;Wu Wei(Basic Medical College of Air Force Medical University of PLA,Xi'an 710032,China;State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shanxi Clinical Research Center for Oral Diseases&Dept,of Oral and Maxillofacial Surgery,Hospital of Stomatology,Air Force Medical University of PLA,Xi'an 710032,China)
出处
《国际口腔医学杂志》
CAS
CSCD
2020年第6期677-685,共9页
International Journal of Stomatology
基金
国家自然科学基金(81771040)。
关键词
3D打印
骨材料
颌面部缺损
修复重建
3D printing
bone materials
maxillofacial defects
restoration
