摘要
目的探讨不同时机有创机械通气在慢性阻塞性肺疾病急性发作合并重度呼吸衰竭中的应用价值。方法选取60例行有创机械通气治疗的慢性阻塞性肺疾病急性发作合并重度呼吸衰竭患者作为研究对象,根据入院先后顺序分为对照组和观察组,每组30例。对照组在出现机械通气指征6 h后进行有创机械通气治疗,观察组则早期(6 h内)进行有创机械通气治疗,比较2组的治疗效果。结果观察组机械通气治疗时间和住院时间短于对照组,并发症发生率低于对照组,生活质量评分高于对照组,差异均有统计学意义(P<0.05);治疗前,2组血气指标比较,差异无统计学意义(P>0.05);治疗后,观察组动脉血氧分压和氧合指数高于对照组,动脉血二氧化碳分压低于对照组,差异均有统计学意义(P<0.05)。结论慢性阻塞性肺疾病急性发作合并重度呼吸衰竭患者尽早进行有创机械通气治疗,可改善血气指标,降低并发症发生率,缩短机械通气治疗时间和住院时间,提高患者的生活质量。
Objective To explore the application value of invasive mechanical ventilation at different time points in treatment of patients with chronic obstructive pulmonary disease combined with severe respiratory failure.Methods A total of 60 invasive mechanical ventilation patients with chronic obstructive pulmonary disease combined with severe respiratory failure were selected as research objects,and were divided into control group and observation group according to the order of admission.The patients in the control group(n=30)were given invasive mechanical ventilation after 6 h of indications for mechanical ventilation,the patients in the observation group(n=30)were given early(6 h)invasive mechanical ventilation therapy,treatment effect of two groups was compared.Results The duration of mechanical ventilation and hospitalization time in the observation group were shorter,the incidence of complications was lower,and the score of quality of life was higher than that in the control group(P<0.05).There were no differences in blood gas indexes between the two groups before treatment(P>0.05).After treatment,arterial partial pressure of oxygen and oxygenation index of the observation group were higher,and arterial partial pressure of carbon dioxide was lower than that of the control group(P<0.05).Conclusion Invasive mechanical ventilation therapy for patients with acute attack of chronic obstructive pulmonary disease complicated with severe respiratory failure can improve the blood gas indexes,reduce the incidence of complications,shorten the duration of mechanical ventilation and hospital stay,and improve the quality of life of the patients.
作者
章淼
张勇
ZHANG Miao;ZHANG Yong(Department of Kidney,Shanyang County People's Hospital,Shangluo,Shaanxi,726400;Department of Digestion,Shanyang County People's Hospital,Shangluo,Shaanxi,726400)
出处
《实用临床医药杂志》
CAS
2020年第16期19-21,25,共4页
Journal of Clinical Medicine in Practice
关键词
有创机械通气
慢性阻塞性肺疾病
急性发作
重度呼吸衰竭
血气指标
并发症
生活质量
invasive mechanical ventilation
chronic obstructive pulmonary disease
acute attack
severe respiratory failure
blood gas indexes
complications
quality of life
