摘要
目的探讨新型冠状病毒肺炎患者入院血压、血清C反应蛋白(CRP)水平对疾病程度及预后的评估价值。方法收集2020年1—2月就诊于本院的73例确诊为新型冠状病毒(2019-nCoV)感染患者的资料,年龄、性别、入院时收缩压、舒张压、CRP、疾病分型、转归情况、住院时间。分别依据患者的转归情况、疾病分型、住院时间分为3个模块,比较各模块各组收缩压、舒张压、脉压、CRP水平;采用Pearson相关性分析确定患者入院时血压、CRP与疾病分型、转归及住院时间的相关性。结果CRP在不同疾病分型间存在差异(P<0.05);入院时的脉压差、CRP在不同住院时间患者间存在显著差异(P<0.05);经Pearson分析,收缩压、脉压差与疾病分型呈正相关;CRP与住院时间呈正相关;疾病转归与收缩压、舒张压、脉压差及CRP间呈负相关(P>0.05);疾病分型方面,患者收缩压>127 mmHg、脉压差≤36 mmHg、CRP>5 mg/L为最佳截断点,灵敏度比较,收缩压>脉压差及CRP,特异性均为100.00%;用于住院时间方面,患者收缩压>126 mmHg、脉压差>54 mmHg、CRP>5 mg/L为最佳截断点,灵敏度比较,CRP>收缩压>脉压差,特异性比较,脉压差>CRP>收缩压,CRP用于疾病分型及住院时间的由线下面积(AUC)均优于收缩压和脉压差。结论新型冠状病毒肺炎患者的入院血压(主要是收缩压、脉压差)、CRP水平能够对疾病程度(分型)及住院时间有一定的预测作用,在护理过程中,应予以重点关注,避免临床护理中不必要的监测忽视。
Objective To explore the evaluation value of hospitalized blood pressure and serum C-reactive protein(CRP)levels in COVID-19 patients on the severity and prognosis of the disease.Methods To collect data including age,gender,hospitalized systolic blood pressure,diastolic blood pressure,CRP,disease classification,prognosis and outcome of disease,and length of stay from 73 cases of patients diagnosed with 2019-nCoV infection who were admitted to our hospital from January to February 2020.According to the patient’s condition,they were divided into three modules such as prognosis and outcome of disease,disease classification,and length of stay to compare the systolic blood pressure,diastolic blood pressure,pulse pressure,and CRP levels of each group.Pearson correlation analysis was used to determine the correlation between hospitalized blood pressure,CRP and disease classification,prognosis and outcome of disease and length of stay.Results The CRP differed among different disease types(P<0.05),pulse pressure difference at admission and CRP were significantly different among patients with different length of hospitalization(P<0.05).Pearson analysis showed that systolic blood pressure and pulse pressure difference were positively correlated with disease classification,CRP and length of stay was positively correlated,and prognosis and outcome of disease was negatively correlated with systolic blood pressure,diastolic blood pressure,pulse pressure difference,and CRP(P>0.05).In terms of disease classification,the patient's systolic blood pressure>127 mmHg,pulse pressure difference≤36 mmHg and CRP>5 mg/L were the best cut-off points,with sensitivity comparison,systolic blood pressure>pulse pressure difference and CRP,and the specificity were both 100.00%.In terms of the length of stay,the patient’s systolic blood pressure>126 mmHg,pulse pressure difference>54 mmHg and CRP>5 mg/L were the best cut-off points,with sensitivity comparison,CRP>systolic blood pressure>pulse pressure difference,with specificity comparison,pulse pressure difference>CRP>systolic blood pressure,the area under the line(AUC)of CRP used for disease classification and length of stay was better than that of systolic blood pressure and pulse pressure difference.Conclusion The hospitalized blood pressure(mainly systolic blood pressure and pulse pressure difference)and CRP levels of patients with COVID-19 can predict the degree of disease(classification)and length of stay in the hospital.Medical staff should be paid special attention during the nursing process to avoid unnecessary monitoring neglect in clinical nursing.
作者
刘翠娟
罗银弟
曾蓓颖
LIU Cui-juan;LUO Yin-di;ZENG Bei-ying
出处
《护理实践与研究》
2020年第17期23-25,共3页
Nursing Practice and Research
