摘要
目的观察中医内科治疗原发性肾病综合征的临床疗效。方法选取2018年1月至2019年1月在本院接受治疗的66例原发性肾病综合征患者作为研究对象,按照治疗方法的不同分为两组,每组33例。对照组给予常规基础治疗,观察组在对照组基础上给予中医内科治疗,比较两组疗效。结果观察组治疗起效时间、症状消失时间、住院时间均短于对照组,差异有统计学意义(P<0.05);观察组治疗有效率为93.94%,明显高于对照组的78.79%(P<0.05);观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05);治疗前,两组实验室检查各项结果比较差异无统计学意义,治疗后,两组24 h尿蛋白、总胆固醇均明显下降,血浆白蛋白及凝血酶原时间均明显上升,且观察组优于对照组,差异有统计学意义(P<0.05)。结论原发性肾病综合征在常规治疗的基础上再给予中医内科治疗,可有效降低不良反应,改善肾脏功能,提高临床疗效,具有重要的研究价值。
Objective To observe the clinical effect of treating primary nephrotic syndrome with internal medicine of traditional Chinese medicine.Methods 66 patients with primary nephrotic syndrome treated in our hospital from January 2018 to January 2019 were selected as study subjects. According to different treatment methods, they were divided into two groups, with 33 cases in each group. The control group was given routine basic treatment, the observation group was given internal medicine treatment of traditional Chinese medicine on the basis of the control group, and the efficacy of the two groups was compared. Results The onset time, symptom disappearance time and hospital stay time of the observation group were shorter than those of the control group, and the difference was statistically significant(P<0.05). The effective rate was 93.94% in the observation group, which was significantly higher than 78.79% in the control group(P<0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group, and the difference was statistically significant(P<0.05). Before treatment, there was no statistically significant difference in the results of laboratory tests between the two groups. After treatment, a 24 h urine protein and total cholesterol of the two groups were significantly decreased, and plasma albumin and prothrombin time were significantly increased, and the observation group was better than the control group, with statistically significant difference(P<0.05). Conclusion On the basis of conventional treatment, internal medicine treatment of primary nephrotic syndrome can effectively reduce adverse reactions, improve renal function and clinical efficacy, which has important research value.
作者
吴雪
段国相
Wu Xue;Duan Guoxiang(Department of Kidney Six,Heilongjiang Academy of Traditional Chinese Medicine,Harbin,Heilongjiang,150001,China;Department of Acupuncture and Moxibustion Six,Heilongjiang Academy of Traditional Chinese Medicine,Harbin,Heilongjiang,150001,China)
出处
《当代医学》
2020年第26期74-76,共3页
Contemporary Medicine
关键词
原发性肾病综合征
基础治疗
中医内科治疗
疗效
Primary nephrotic syndrome
Basic treatment
Medical treatment of traditional Chinese medicine
Curative effect
