摘要
目的:观察理中汤联合双歧杆菌四联活菌片治疗腹泻型胃肠功能紊乱的临床疗效。方法:选取腹泻型胃肠功能紊乱患者100例,按随机数字表法分为观察组和对照组各50例。对照组给予双歧杆菌四联活菌片治疗,观察组给予理中汤联合双歧杆菌四联活菌片治疗。评定2组的临床疗效,检测2组患者治疗前后血清免疫指标及炎症因子水平。结果:观察组总有效率为98.00%,高于对照组86.00%,差异有统计学意义(P<0.05)。治疗前,2组血清C-反应蛋白(CRP)、白细胞介素-6 (IL-6)水平比较,差异无统计学意义(P>0.05)。治疗后,2组血清CRP、IL-6水平较治疗前降低,且观察组血清CRP、IL-6水平低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组CD3+、CD4+、CD8+水平比较,差异无统计学意义(P>0.05)。治疗后,2组CD3+、CD4+、CD8+水平较治疗前升高,且观察组CD3+、CD4+、CD8+水平高于对照组,差异均有统计学意义(P<0.05)。结论:理中汤联合双歧杆菌四联活菌片治疗腹泻型胃肠功能紊乱患者的临床效果较好,可以改善患者免疫功能,降低炎症因子水平。
Objective:To observe the clinical effect of Lizhong tang combined with bifidobacterium tetravaccine tablets for patients with diarrhea-predominant gastrointestinal dysfunction. Methods:A total of 100 cases of patients with diarrheapredominant gastrointestinal dysfunction were selected and divided into the observation group and the control group according to the random number table method,50 cases in each group. The control group was treated with bifidobacterium tetravaccine tablets,and the observation group was additionally treated with Lizhong tang based on the treatment of the control group.The clinical effect in the two groups was evaluated. Before and after treatment, the changes of the indexes of immune function in serum as well as the levels of inflammatory factors in the two groups were detected. Results:The total effective rate was 98.00% in the observation group,higher than that of 86.00% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of the levels of C-reactive protein(CRP) and interleukin-6(IL-6) in serum between the two groups(P>0.05). After treatment,the levels of CRP and IL-6 in serum in the two groups were decreased when compared with those before treatment, and the above levels in the observation group were lower than those in the control group, differences being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of the levels of CD3+,CD4+and CD8+between the two groups(P>0.05). After treatment,the levels of CD3+,CD4+and CD8+in the two groups were increased when compared with those before treatment, and the above levels in the observation group were higher than those in the control group,differences being significant(P<0.05). Conclusion:The therapy of Lizhong tang combined with bifidobacterium tetravaccine tablets has good clinical effect in treating patients with diarrhea-predominant gastrointestinal dysfunction,which can improve the immune function of patients,reduce the levels of inflammatory factors.
作者
尚素芬
孔明
石梅英
李红霞
SHANG Sufen;KONG Ming;SHI Meiying;LI Hongxia
出处
《新中医》
CAS
2020年第14期42-44,共3页
New Chinese Medicine
关键词
腹泻型胃肠功能紊乱
理中汤
双歧杆菌四联活菌片
免疫功能
炎症因子
Diarrhea-predominant gastrointestinal dysfunction
Lizhong tang
Bifidobacterium tetravaccine tablets
Immune function
Inflammatory factors
