摘要
目的 研究头孢唑肟钠联合莫西沙星治疗社区获得性肺炎的临床疗效及不良反应.方法 100例社区获得性肺炎患者,随机分为对照组和观察组,每组50例.对照组患者采用头孢唑肟钠治疗,观察组采用头孢唑肟钠联合莫西沙星治疗.对比两组患者的临床疗效、胸痛改善情况及不良反应发生情况.结果 观察组患者治疗总有效率为92.0%,明显高于对照组的76.0%,差异有统计学意义(P<0.05).观察组患者胸痛缓解率98.0%高于对照组的86.0%,差异有统计学意义(P<0.05).观察组患者不良反应发生率8.0%明显低于对照组的24.0%,差异有统计学意义(P<0.05).结论 头孢唑肟钠联合莫西沙星治疗社区获得性肺炎的临床疗效显著,有助于减轻胸痛情况,降低不良反应的发生,可在临床上进行推广应用.
Objective To study the clinical efficacy and adverse reactions of cefazoxime sodium combined with moxifloxacin in the treatment of community acquired pneumonia.Methods A total of 100 patients with community acquired pneumonia were randomly divided into control group and observation group,with 50 cases in each group.The control group was treated by cefazoxime sodium,and the observation group was treated by cefazoxime sodium combined with moxifloxacin.The clinical efficacy,improvement of chest pain,and occurrence of complications were compared between the two groups.Results The total effective rate of treatment of the observation group was 92.0%,which was obviously higher than that of the control group 76.0%,and the difference was statistically significant(P<0.05).The improvement rate of chest pain 98.0%of the observation group was higher than that of the control group 86.0%,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 8.0%of the observation group was obviously lower than that of the control group 24.0%,and the difference was statistically significant(P<0.05).Conclusion Cefazoxime sodium combined with moxifloxacin shows remarkable clinical efficacy in the treatment of community acquired pneumonia,which can help relieve chest pain and reduce the incidence of adverse reactions.It can be promoted and applied in the clinic practice.
作者
张静
杨廷勇
ZHANG Jing;YANG Ting-yong(Yicheng Gushao Town Health Center,Zaozhuang 277313,China)
出处
《中国现代药物应用》
2020年第13期148-150,共3页
Chinese Journal of Modern Drug Application
关键词
头孢唑肟钠
莫西沙星
社区获得性肺炎
不良反应
Cefazoxime sodium
Moxifloxacin
Community acquired pneumonia
Adverse reactions
