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晚期非小细胞肺癌患者营养状况及其影响因素调查 被引量:16

Investigation of nutritional status and its influencing factors in patients with advanced non-small cell lung cancer
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摘要 目的调查晚期非小细胞肺癌患者的营养状况,分析营养不良的影响因素。方法 2015年7月~2016年8月,对象为就诊于我院的晚期非小细胞肺癌患者,采取一般资料调查表和患者主观整体评估(PG-SGA)进行调查评估。结果在270例晚期非小细胞肺癌患者中,共计存在营养不良(PG-SGA B+PG-SGA C)的患者有172例(63.7%),而重度营养不良(PG-SGA C)患者在其中存在55例(20.4%)。不同年龄组、临床分期、卡氏评分(KPS评分)和体质指数的患者之间营养状况存在差异(P<0.05)。进一步多因素分析发现,临床分期、体质指数和KPS评分是影响非小细胞肺癌患者营养状况的因素。结论在晚期非小细胞肺癌患者中,发生营养不良的概率为63.7%,在临床中尽早行营养评估,及时干预。临床分期、体质指数、KPS评分是引发非小细胞肺癌患者营养不良的主要因素。 Objective To investigate the nutritional status of patients with advanced non-small cell lung cancer(NSCLC),and to analyze the influencing factors of malnutrition.Methods From July 2015 to August 2016,it selected advanced non-small cell patients in our hospital as the study object.In this study,the nutritional status of the selected patients was investigated and evaluated by general situation questionnaire and patients subjective overall assessment scale(PG-SGA).Results Of 270 patients with advanced NSCLC,172(63.7%)had malnutrition(PG-SGA B+PG-SGA C),while 55(20.4%)had severe malnutrition(PG-SGA C).The nutritional status of NSCLC patients with different age,clinical stages,KPS scores and BMI was abnormal,which was statistically significant(P<0.05).Multivariate logistic regression analysis showed that clinical stage,KPS score and BMI were the factors affecting the nutritional status of NSCLC patients.Conclusion From this study,we can see that 63.7%of the patients with advanced non-small cell lung cancer suffer from malnutrition,which is poor.It is necessary to carry out nutrition assessment as early as possible in clinical practice and intervene according to the actual situation.The main causes of malnutrition in non-small cell lung cancer patients are clinical stage,KPS score and BMI.
作者 邢影 董量 付浩宇 张凤珍 王志武 杨俊泉 XING Ying;DONG Liang;FU Hao-yu;ZHANG Feng-zhen;WANG Zhi-wu;YANG Jun-quan(Tangshan People's Hospital,Tangshan,Hebei 063001,China)
机构地区 唐山市人民医院
出处 《临床肺科杂志》 2020年第7期1013-1016,共4页 Journal of Clinical Pulmonary Medicine
基金 河北省医学科学研究重点课题计划(No.20171286)。
关键词 非小细胞肺癌 营养状况 影响因素 PG-SGA non-small cell lung cancer nutritional status influencing factors patient-generated subjective global assessment
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